Developmental Center for Clinical and Translational Science in Chiropractic

Palmer Center for Chiropractic Research（PCCR）建议建立一个为期4年的多学科 发展中心，以提高我们正在进行的研究计划的水平和质量，通过提高我们的 开展临床研究的能力，推进科学专业知识和研究基础设施，并支持 帕尔默脊椎按摩学院的10名研究人员加强了沟通和合作， 爱荷华州大学、西奈山医疗中心、Mines VA医院（VA）和洛约拉大学斯特里奇学院 药随着我们超越强大的平台， 我们正在建立基础研究，以实现我们建立强大的转化研究的总体目标。 中心脊椎治疗，我们的基础和临床脊椎治疗研究直接相关， 改善人类健康。这个发展中心的目的是研究互补和 替代医学（DCRC 1）申请，题为“临床和转化发展中心” 脊椎指压治疗研究”旨在建立我们在临床研究方面的专业知识，并作为重点， 加强和促进我们与这些传统机构的既有和不断发展的关系， 从而促进3个协同和新颖的研究项目。本DCRC I的中心科学主题 应用是为了评估颈椎和相关的非旋转脊椎按摩脊柱操作（SM） 功能障碍这种方法的长期重要性在于它为以下方面提供了有价值的信息： 了解脊柱推拿在我们不断发展的医疗保健系统中的适当临床作用。我们将 也有助于发展模式，严格进行临床和转化研究 涉及操纵技巧项目1是一项II期研究，旨在观察上颈椎 推拿手法对I期高血压患者降压作用的研究项目2是一个 R21型研究，探讨机械辅助手法治疗 颞下颌关节紊乱项目3是一项R21型研究，旨在开发和评估一种假操作， 使用临床和生物力学组件的颈椎。项目将得到 诊所和数据管理核心，以及管理核心。研究者将使用试点数据提交 有竞争力的拨款申请NIH，并将提供研究培训经验，为未来的CAM investigators.在第一阶段发展局的支持下，委员会将在以下方面取得更大进展： 建立正式的合作伙伴关系，在CAM领域开展严格的高质量临床研究， 目标是创建一个脊椎按摩疗法的转化研究项目。

Palmer Center for Chiropractic Research (PCCR) proposes to establish a 4-year multidisciplinary Developmental Center to increase the level and quality of our ongoing research program by enhancing our ability to conduct clinical research, to advance scientific expertise and research infrastructure, and to support enhanced communication and partnering among 10 investigators at Palmer College of Chiropractic, the University of Iowa, Mt Sinai Medical Center, Mines VA Hospital (VA), and Loyola University Stritch School of Medicine. It is the logical next step in the development of the PCCR as we move beyond the strong platform we are building in basic research toward our overarching goal of establishing a strong translational research center for chiropractic where our basic and clinical chiropractic research studies are directly relevant to improving human health. The purpose of this Developmental Center for Research on Complementary and Alternative Medicine (DCRC 1) application entitled "Developmental Center for Clinical and Translational Research in Chiropractic," is to build our expertise in clinical research and to serve as the focal point to strengthen and enhance our established and evolving relationships with these conventional institutions and thereby facilitate 3 synergistic and novel research projects. The central scientific theme of this DCRC I application is to evaluate non-rotary chiropractic spinal manipulation (SM) for cervical spine and related dysfunctions. The long range importance of this approach is that it provides valuable information for understanding the appropriate clinical role of spinal manipulation in our evolving healthcare system. We will also contribute to the development of models for the rigorous conduct of clinical and translational research involving manipulative techniques. Project 1 is a phase II study looking at the effect of upper cervical manipulation techniques in lowering blood pressure in patients with Stage I hypertension. Project 2 is an R21-type study investigating the effect of a mechanically assisted manipulative technique used for treating temporomandibular disorder. Project 3 is an R21-type study to develop and evaluate a sham manipulation in the cervical spine using both a clinical and a biomechanical component. Projects will be supported by the Clinic and Data Management Core, and the Administration Core. Investigators will use pilot data to submit competitive grant applications to NIH, and will provide research training experiences for future CAM investigators. With the support of this DCRC I, the PCCR will be poised to make additional progress in building formal partnerships to undertake rigorous high-quality clinical research in CAM, with the ultimate goal of creating a translational research program in chiropractic.