Developmental Center for Clinical and Translational Science in Chiropractic

帕尔默脊椎疗法研究中心(PCCR)建议建立为期4年的多学科 发展中心通过加强我们的 有能力进行临床研究，推进科学专长和研究基础设施，并支持 加强帕尔默脊椎按摩学院10名研究人员之间的沟通和合作 爱荷华大学、西奈山医学中心、退伍军人医院(VA)和洛约拉大学斯特里奇学院 医学。随着我们超越强大的平台，这是PCCR发展的合乎逻辑的下一步 我们正在基础研究的基础上，朝着建立强大的翻译研究的总体目标前进 脊椎疗法中心，我们的基础和临床脊椎疗法研究直接与 改善人类健康。这个互补性和互补性研究发展中心的目的是 另类医学(DCRC1)申请，题为“临床和翻译发展中心” 脊椎疗法研究“是建立我们在临床研究方面的专业知识，并作为焦点 加强和加强我们与这些传统机构的已建立和不断发展的关系 从而促进3个协同和新颖的研究项目。这次DCRC的中心科学主题是 非旋转脊椎手法(SM)在颈椎及相关疾病中的应用 功能障碍。这种方法的长期重要性在于，它提供了有价值的信息 了解脊柱手法在我们不断发展的医疗体系中的适当临床作用。我们会 还有助于开发严格进行临床和转化性研究的模型 涉及到操控技巧。项目1是第二阶段的研究，旨在观察上颈椎的影响。 手法手法对I期高血压患者的降压作用。项目2是一个 机械辅助手法治疗的R21型研究 颞下颌关节紊乱病。项目3是一项R21类型的研究，旨在开发和评估 使用临床和生物力学组件的颈椎。项目将由 临床和数据管理核心，以及管理核心。调查人员将使用试点数据提交 向NIH提出竞争性拨款申请，并将为未来的CAM提供研究培训经验 调查人员。在《第一次审查报告》的支持下，专责委员会将在以下方面取得更大进展 建立正式的合作伙伴关系，在CAM中进行严格的高质量临床研究，最终 创建脊椎疗法翻译研究项目的目标。

Palmer Center for Chiropractic Research (PCCR) proposes to establish a 4-year multidisciplinary Developmental Center to increase the level and quality of our ongoing research program by enhancing our ability to conduct clinical research, to advance scientific expertise and research infrastructure, and to support enhanced communication and partnering among 10 investigators at Palmer College of Chiropractic, the University of Iowa, Mt Sinai Medical Center, Mines VA Hospital (VA), and Loyola University Stritch School of Medicine. It is the logical next step in the development of the PCCR as we move beyond the strong platform we are building in basic research toward our overarching goal of establishing a strong translational research center for chiropractic where our basic and clinical chiropractic research studies are directly relevant to improving human health. The purpose of this Developmental Center for Research on Complementary and Alternative Medicine (DCRC 1) application entitled "Developmental Center for Clinical and Translational Research in Chiropractic," is to build our expertise in clinical research and to serve as the focal point to strengthen and enhance our established and evolving relationships with these conventional institutions and thereby facilitate 3 synergistic and novel research projects. The central scientific theme of this DCRC I application is to evaluate non-rotary chiropractic spinal manipulation (SM) for cervical spine and related dysfunctions. The long range importance of this approach is that it provides valuable information for understanding the appropriate clinical role of spinal manipulation in our evolving healthcare system. We will also contribute to the development of models for the rigorous conduct of clinical and translational research involving manipulative techniques. Project 1 is a phase II study looking at the effect of upper cervical manipulation techniques in lowering blood pressure in patients with Stage I hypertension. Project 2 is an R21-type study investigating the effect of a mechanically assisted manipulative technique used for treating temporomandibular disorder. Project 3 is an R21-type study to develop and evaluate a sham manipulation in the cervical spine using both a clinical and a biomechanical component. Projects will be supported by the Clinic and Data Management Core, and the Administration Core. Investigators will use pilot data to submit competitive grant applications to NIH, and will provide research training experiences for future CAM investigators. With the support of this DCRC I, the PCCR will be poised to make additional progress in building formal partnerships to undertake rigorous high-quality clinical research in CAM, with the ultimate goal of creating a translational research program in chiropractic.