Diabetes Initiative for Applied Biomedical Engineering

应用生物医学工程糖尿病倡议

• 批准号: 6936568
• 负责人: BRIAN L DAVIS
• 金额: $ 10.41万
• 依托单位: CLEVELAND CLINIC LERNER COM-CWRU
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-07-01 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6936568
• 关键词: bioengineering /biomedical engineering; bioimaging /biomedical imaging; clinical research; curriculum; diabetes mellitus; diabetes mellitus therapy; human subject; interdisciplinary collaboration; mathematical model; medical education; tissue engineering; training

DESCRIPTION (provided by applicant): Close collaboration between engineers and clinicians is essential for state-of-the-art diabetes research, e.g., islet cell transplantation, inhaled insulin technologies, magnetic microsphere delivery devices and stress analyses of the plantar (epi)dermis. Cleveland State University (CSU) and The Cleveland Clinic Foundation (CCF) have successfully collaborated since 1998 on a doctoral program in Applied Biomedical Engineering (ABE) to groom graduate biomedical engineers for careers in industry or applied research. The curriculum enables ABE graduates to conceptualize complex problems at the medicine-engineering interface; understand medical device design and development; work in multidisciplinary settings; and show versatility in moving from fundamental concept to problem solution. The ABE program leverages CSU's strengths in applied engineering and CCF's clinical capabilities. This proposal seeks to extend the ABE effort with a "Diabetes Initiative for Applied Biomedical Engineering Technologies" (DIABET), which will train students to apply their engineering skills to diabetic complications, e.g., cardiovascular disease, diabetic foot pathologies, and peripheral vascular disease. Teams of CCF/CSU faculty will address topics including artificial pancreas designs, insulin-delivery methods, vascular grafts and advanced biomaterials. The proposed curriculum will focus on the emerging fields of bioMEMS, tissue engineering, mathematical modeling, and medical imaging, integrated to give engineers the insights needed to advance the field of applied biomedical engineering within the context of understanding and treating diabetes. Along with new courses, DIABET will facilitate interactions among medical residents, research fellows and graduate engineering students, giving students first-hand experience of issues in the current management of diabetes and providing clinicians access to engineers experienced in cutting-edge technologies. Leading biomedical engineering researchers, physician experts in treating diabetes, and educators will collaborate, with advice from an external advisory board comprising laypersons with a personal interest in diabetes and senior faculty with proven track records in science and medicine. The proposed curriculum will become an educational model for ensuring that graduates master the requisite skills to contribute to teams focused on conquering the devastating consequences of diabetes.

描述(由申请人提供)： 工程师和临床医生之间的密切合作对于最先进的糖尿病研究至关重要，例如胰岛细胞移植、胰岛素吸入技术、磁性微球给药装置和足底(EPI)真皮的应力分析。克利夫兰州立大学(CSU)和克利夫兰临床基金会(CCF)自1998年以来一直在应用生物医学工程(ABE)博士项目上成功合作，以培养工业或应用研究领域的研究生生物医学工程师。该课程使安倍毕业生能够在医学工程界面上概念化复杂的问题；了解医疗器械的设计和开发；在多学科环境中工作；并展示从基本概念到问题解决方案的多才多艺。ABE项目利用了CSU在应用工程方面的优势和CCF的临床能力。 这项提议旨在通过“糖尿病应用生物医学工程技术倡议”(Diabet)来扩展安倍的努力，该计划将培训学生将他们的工程技能应用于糖尿病并发症，例如心血管疾病、糖尿病足部病理和外周血管疾病。CCF/CSU教员团队将讨论包括人工胰腺设计、胰岛素输送方法、血管移植和先进生物材料在内的主题。拟议的课程将专注于生物MEMS、组织工程、数学建模和医学成像等新兴领域，整合这些领域，为工程师提供在理解和治疗糖尿病的背景下推进应用生物医学工程领域所需的洞察力。 除了新的课程，Diabet还将促进住院医师、研究员和工程学研究生之间的互动，让学生对当前糖尿病管理中的问题有第一手体验，并让临床医生接触到在尖端技术方面经验丰富的工程师。领先的生物医学工程研究人员、治疗糖尿病的内科专家和教育工作者将在外部咨询委员会的建议下进行合作，该委员会由对糖尿病有个人兴趣的非专业人士和在科学和医学方面有良好记录的高级教员组成。拟议的课程将成为一种教育模式，确保毕业生掌握必要的技能，为专注于克服糖尿病毁灭性后果的团队做出贡献。