Diabetes Initiative for Applied Biomedical Engineering

应用生物医学工程糖尿病倡议

• 批准号: 7088991
• 负责人: BRIAN L DAVIS
• 金额: $ 10.37万
• 依托单位: CLEVELAND CLINIC LERNER COM-CWRU
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-07-01 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7088991
• 关键词: bioengineering /biomedical engineering; bioimaging /biomedical imaging; clinical research; curriculum; diabetes mellitus; diabetes mellitus therapy; human subject; interdisciplinary collaboration; mathematical model; medical education; tissue engineering; training

DESCRIPTION (provided by applicant): Close collaboration between engineers and clinicians is essential for state-of-the-art diabetes research, e.g., islet cell transplantation, inhaled insulin technologies, magnetic microsphere delivery devices and stress analyses of the plantar (epi)dermis. Cleveland State University (CSU) and The Cleveland Clinic Foundation (CCF) have successfully collaborated since 1998 on a doctoral program in Applied Biomedical Engineering (ABE) to groom graduate biomedical engineers for careers in industry or applied research. The curriculum enables ABE graduates to conceptualize complex problems at the medicine-engineering interface; understand medical device design and development; work in multidisciplinary settings; and show versatility in moving from fundamental concept to problem solution. The ABE program leverages CSU's strengths in applied engineering and CCF's clinical capabilities. This proposal seeks to extend the ABE effort with a "Diabetes Initiative for Applied Biomedical Engineering Technologies" (DIABET), which will train students to apply their engineering skills to diabetic complications, e.g., cardiovascular disease, diabetic foot pathologies, and peripheral vascular disease. Teams of CCF/CSU faculty will address topics including artificial pancreas designs, insulin-delivery methods, vascular grafts and advanced biomaterials. The proposed curriculum will focus on the emerging fields of bioMEMS, tissue engineering, mathematical modeling, and medical imaging, integrated to give engineers the insights needed to advance the field of applied biomedical engineering within the context of understanding and treating diabetes. Along with new courses, DIABET will facilitate interactions among medical residents, research fellows and graduate engineering students, giving students first-hand experience of issues in the current management of diabetes and providing clinicians access to engineers experienced in cutting-edge technologies. Leading biomedical engineering researchers, physician experts in treating diabetes, and educators will collaborate, with advice from an external advisory board comprising laypersons with a personal interest in diabetes and senior faculty with proven track records in science and medicine. The proposed curriculum will become an educational model for ensuring that graduates master the requisite skills to contribute to teams focused on conquering the devastating consequences of diabetes.

描述（由申请人提供）： 工程师和临床医生之间的密切合作对于最先进的糖尿病研究至关重要，例如，胰岛细胞移植、吸入胰岛素技术、磁性微球递送装置和足底（表皮）真皮的应力分析。克利夫兰州立大学（CSU）和克利夫兰诊所基金会（CCF）自1998年以来成功地合作了应用生物医学工程（ABE）博士课程，以培养毕业的生物医学工程师从事工业或应用研究。该课程使ABE毕业生能够在医学工程界面概念化复杂问题;了解医疗器械设计和开发;在多学科环境中工作;并在从基本概念到问题解决方案的转变中表现出多功能性。ABE计划利用了CSU在应用工程和CCF临床能力方面的优势。 该提案旨在通过“糖尿病应用生物医学工程技术倡议”（DIABET）扩展ABE的工作，该倡议将培训学生将其工程技能应用于糖尿病并发症，例如，心血管疾病、糖尿病足病变和外周血管疾病。CCF/CSU教师团队将讨论的主题包括人工胰腺设计，胰岛素输送方法，血管移植和先进的生物材料。拟议的课程将侧重于bioMEMS，组织工程，数学建模和医学成像的新兴领域，综合为工程师提供在理解和治疗糖尿病的背景下推进应用生物医学工程领域所需的见解。 沿着新课程，DIABET将促进住院医师，研究员和工程研究生之间的互动，为学生提供当前糖尿病管理问题的第一手经验，并为临床医生提供接触尖端技术经验丰富的工程师的机会。领先的生物医学工程研究人员，治疗糖尿病的医生专家和教育工作者将合作，由一个外部咨询委员会提供建议，该委员会由对糖尿病有个人兴趣的外行和在科学和医学方面有良好记录的高级教师组成。拟议的课程将成为一个教育模式，以确保毕业生掌握必要的技能，以促进团队专注于征服糖尿病的破坏性后果。