How are axons guided to their targets in the developing nervous system?
How are axons guided to their targets in the developing nervous system?
批准号:
nhmrc : 1107986
负责人:
Prof Geoffrey Goodhill
金额:
$22.55万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2018-12-31
中文摘要
许多神经发育障碍可能是神经连接缺陷的结果。在这个项目中,我们将使用新技术来研究生长的神经纤维在发育过程中是如何引导到它们的目标的,并使用这些数据来创建新的数学模型,该模型可以预测神经纤维在不同情况下的生长方式。这将促进我们对大脑正常和异常发育的机制的理解。
英文摘要
Many neurodevelopmental disorders are probably the result of wiring defects. In this project we will use new technologies to study how growing nerve fibres are steered to their targets during development, and use this data to create new mathematical models which can predict which way nerve fibres should grow in different situations. This will advance our understanding of the mechanisms underlying both normal and abnormal brain development.
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依托单位:
海外基金