SAfrica Infectious Disease Clinical Res.Training Program

描述（由申请人提供）：非洲面临的医疗挑战是世界上最极端的。非洲面临的疾病是国际社会直接关注的问题，因为非洲的大多数卫生负担在本质上是传染性的。南非正面临着世界上最严重的结核病流行之一，其发病率是其他发展中国家的两倍多，比目前在美国或西欧看到的发病率高出60倍。如果要改善这种情况，重点突出和可持续的临床研究至关重要，南非必须具备在传染病方面进行大规模社区试验的能力。不幸的是，这并不是这个国家目前的状况。由不同的美国和国际赞助商支持的项目通过提供研究伦理课程，鼓励追求基础科学和/或公共卫生方面的研究生证书或高级学位，提供导师帮助年轻科学家回国后，发展沟通和支持网络，并提供执行诊断和分子生物学程序所需技术的专业培训来提供帮助。然而，这些项目主要面向高级研究人员，并且往往要求研究人员参加其他国家的培训。此外，临床研究团队的其他成员很少有正式的培训选择，这些人通常没有机会和资源去追求专业发展，无论是在国内还是在国际上。南非传染病临床研究培训计划（sayedcrtp）的目标是首先在开普敦大学（UCT）的整个临床研究团队以及开普敦大学附属的其他机构中建立可持续的研究能力，在南非开展与传染病，特别是结核病有关的大型社区临床研究。

DESCRIPTION (provided by applicant): The medical challenges facing Africa are among the most extreme in the world. The diseases faced by Africa are of direct concern to the global community, since most of Africa's health burden is infectious in nature. South Africa is facing one of the worst tuberculosis epidemics in the world, with disease rates more than double those observed in other developing countries, and up to 60 times higher than those currently seen in the USA or Western Europe. Focused and sustainable clinical research is critical if the situation is to improve, and South Africa must possess the capacity to conduct large community trials in infectious diseases. Unfortunately, this is not presently the state of affairs in this country. Programs supported from different U.S. and international sponsors have assisted by providing courses in research ethics, encouraging the pursuit of graduate certificates or advanced degrees in the basic sciences and/or public health, providing mentors to assist young scientists upon return to their home countries, developing networks for communication and support, and offering specialized training in the performance of techniques necessary to perform diagnostic and molecular biology procedures. However, these are mostly geared to senior researchers and often require investigators to attend training in other countries. In addition, few formal training options are available for other members of the clinical research team, and these individuals usually have little opportunity and resources to pursue professional development, either in-country or at international offerings. The goal of the South Africa Infectious Disease Clinical Research Training Program (SAIDCRTP) is to build sustainable research capacity firstly within the total clinical research teams at the University of Cape Town (UCT), and other institutions affiliated with UCT, in the execution of large community-based clinical research related to infectious diseases, and in particular tuberculosis, in South Africa.