The South African Infectious Disease Clinical Research Training Program

描述(申请人提供)：南非正面临着世界上最严重的结核病流行之一，其发病率是其他发展中国家的两倍多，比目前美国或西欧的发病率高出60倍。如果情况要有所改善，重点和可持续的临床研究是至关重要的，南非必须拥有在传染病方面进行大规模社区试验的能力。不幸的是，良好的临床研究风气并不是这个国家的现状。由不同的美国和国际赞助商支持的项目正在通过提供研究伦理课程、鼓励攻读基础科学和/或公共卫生方面的研究生证书或高级学位，以及提供执行诊断和分子生物学程序所需技术方面的专门培训来提供帮助。然而，这些项目大多面向高级研究人员，往往需要调查人员到其他国家参加培训。临床研究团队的其他成员几乎没有正式的发展选择，这些人通常几乎没有机会和资源来追求专业发展，无论是在国内还是在国际上。南非传染病临床研究培训计划(SAIDCRTP)的长期目标是在整个临床研究团队中建立可持续的传染病研究能力。为了实现这一目标，SAIDCRTP将1)在开普敦大学(UCT)内建立可持续的研究能力，2)在开普敦大学创建临床研究管理硕士学位课程，3)向其他南非人提供临床研究能力建设。这项申请与南非公民的公共健康高度相关。通过实现其目标和目标，SAIDCRTP将加强南非优秀临床研究的执行力，并通过专业发展计划和高质量的学术硕士学位计划扩大临床研究的教育机会。

DESCRIPTION (provided by applicant): South Africa is facing one of the worst tuberculosis epidemics in the world, with disease rates more than double those observed in other developing countries, and up to 60 times higher than those currently seen in the USA or Western Europe. Focused and sustainable clinical research is critical if the situation is to improve, and South Africa must possess the capacity to conduct large community trials in infectious diseases. Unfortunately, a sound clinical research ethos is not the state of affairs in this country. Programs supported from different U.S. and international sponsors are assisting by providing courses in research ethics, encouraging the pursuit of graduate certificates or advanced degrees in the basic sciences and/or public health, and offering specialized training in the performance of techniques necessary to perform diagnostic and molecular biology procedures. However, these are mostly geared to senior researchers and often require investigators to attend training in other countries. Few formal development options are available for other members of the clinical research team, and these individuals usually have little opportunity and resources to pursue professional development, either in-country or at international offerings. The long-term goal of the South Africa Infectious Disease Clinical Research Training Program (SAIDCRTP) is to build sustainable research capacity in infectious diseases within the total clinical research team. To accomplish this, SAIDCRTP will 1) build sustainable research capacity within the University of Cape Town (UCT), 2) create a masters degree program in clinical research administration at UCT, and 3) offer capacity building in clinical research to other South Africans. This application is highly relevant to the public health of South African citizens. By accomplishing its goal and objectives, SAIDCRTP will enhance the execution of good clinical research performed by South Africans, and expand education opportunities in clinical research through a professional development program and a high-quality academic masters degree program.