Development of multi-functional cyclic peptide probes

多功能环肽探针的研制

• 批准号: 2599253
• 金额: --
• 依托单位: Newcastle University
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2021
• 资助国家: 英国
• 起止时间: 2021 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2599253
• 关键词: Development; multi; functional; cyclic; peptide

This project provides an exciting opportunity to develop new peptide-based targeting approaches for chemical biology and drug discovery. The student will be based in the recently refurbished state-of-the-art chemical biology laboratories in the Bedson building at Newcastle University, and will work alongside a team of experienced chemists, chemical biologists and molecular/cell biologists. The student will receive extensive training in cutting-edge methods in chemical biology, including encoded library technologies, peptide chemistry / synthetic chemistry, biophysical and biochemical and cellular assays, and will be supported by academic and industrial supervisors. The student will work closely with NovoNordisk, a global pharmaceutical company specialising in diabetes care and peptide therapeutics discovery. The student will have the opportunity to visit NovoNordisk in Copenhagen, Denmark, for industrial placements during the course of their PhD.

该项目为化学生物学和药物发现开发新的基于多肽的靶向方法提供了一个令人兴奋的机会。这名学生将在纽卡斯尔大学贝德森大楼最近翻新的最先进的化学生物学实验室工作，并将与一个由经验丰富的化学家、化学生物学家和分子/细胞生物学家组成的团队一起工作。学生将接受化学生物学尖端方法的广泛培训，包括编码库技术、肽化学/合成化学、生物物理和生化以及细胞分析，并将得到学术和工业主管的支持。这名学生将与诺和诺德密切合作，诺和诺德是一家专门从事糖尿病护理和多肽疗法发现的全球制药公司。在攻读博士学位期间，该学生将有机会访问丹麦哥本哈根的诺和诺德公司，进行工业实习。