ABI 3730 Capillary Sequencers

ABI 3730 毛细管测序仪

基本信息

项目摘要

DESCRIPTION (provided by applicant): In the post human genomic era, genetic information and functional assays of gene expression have become indispensable for a significant fraction of NIH-funded research. We are requesting funds to purchase two automated capillary sequencers to improve sequencing operations provided by the University of Illinois at Urbana-Champaign's W. M. Keck Center for Comparative and Functional Genomics. New sequencers have greatly improved throughput, reliability, performance, and are operated at greatly reduced costs for labor, consumables, and maintenance. These cost savings will be reflected in lower sequencing costs for users, stretching NIH-funded lab's budgets, and producing shorter turnaround times and higher quality data. Also, as the cost of operating and maintaining aging sequencers increases, upgrading to more efficient and economical sequencers becomes essential. With the funding of several NIH-funded functional genomics projects at the UIUC, the continuous increase in sequencing services performed since the establishment of the Keck Center, and the major expansion of campus biomedical researchers with the establishment of the UIUC Post-Genomic Institute, large increases in our sequencing needs are occurring. The Keck Center's High Throughput Sequencing and Genotyping lab is part of an integrated genomics facility providing comprehensive, state-of-the-art instrumentation, consultation, and training opportunities for researchers, and occupies a unique niche not provided by large sequencing centers.
描述(由申请人提供):在后人类基因组时代,基因表达的遗传信息和功能测定已成为NIH资助研究的重要组成部分。我们正在申请资金购买两台自动毛细管测序仪,以改善伊利诺伊大学香槟分校的W。M.凯克比较和功能基因组学中心。新的测序仪大大提高了通量、可靠性和性能,并以大大降低的劳动力、耗材和维护成本进行操作。这些成本节约将体现在用户的测序成本降低,NIH资助的实验室预算增加,以及生产更短的周转时间和更高质量的数据。此外,随着操作和维护老化测序仪的成本增加,升级到更高效和更经济的测序仪变得至关重要。随着几个NIH资助的功能基因组学项目在UIUC的资金,在测序服务的持续增加进行自凯克中心成立以来,和校园生物医学研究人员的重大扩张与UIUC后基因组研究所的建立,在我们的测序需求大幅增加正在发生。 凯克中心的高重复测序和基因分型实验室是一个综合基因组学设施的一部分,为研究人员提供全面的,最先进的仪器,咨询和培训机会,并占据了大型测序中心所不提供的独特利基。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Jonathan V. Sweedler其他文献

Proteoform profiling of endogenous single cells from rat hippocampus at scale
大规模大鼠海马体来源的内源性单细胞蛋白质组学分析
  • DOI:
    10.1038/s41587-025-02669-x
  • 发表时间:
    2025-05-15
  • 期刊:
  • 影响因子:
    41.700
  • 作者:
    Pei Su;Michael A. R. Hollas;Indira Pla;Stanislav Rubakhin;Fatma Ayaloglu Butun;Joseph B. Greer;Bryan P. Early;Ryan T. Fellers;Michael A. Caldwell;Jonathan V. Sweedler;Jared O. Kafader;Neil L. Kelleher
  • 通讯作者:
    Neil L. Kelleher
Neurochemical challenge
  • DOI:
    10.1007/s00216-006-0932-1
  • 发表时间:
    2006-11-18
  • 期刊:
  • 影响因子:
    3.800
  • 作者:
    Michael L. Heien;Jonathan V. Sweedler
  • 通讯作者:
    Jonathan V. Sweedler
Top-down Proteomics of 10,000 Single Brain Cells
10,000 个单个脑细胞的自上而下蛋白质组学
  • DOI:
  • 发表时间:
    2023
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Pei;Michael A. R. Hollas;S. Rubakhin;F. Butun;Joseph B. Greer;Bryan P. Early;Ryan T. Fellers;Michael A Caldwell;Jonathan V. Sweedler;Jared O. Kafader;N. Kelleher
  • 通讯作者:
    N. Kelleher
Isoaspartate-containing galanin in rat hypothalamus
大鼠下丘脑中含异天冬氨酸的甘丙肽
  • DOI:
    10.1038/s42004-025-01475-5
  • 发表时间:
    2025-03-08
  • 期刊:
  • 影响因子:
    6.200
  • 作者:
    Samuel Okyem;David H. Mast;Elena V. Romanova;Stanislav S. Rubakhin;Jonathan V. Sweedler
  • 通讯作者:
    Jonathan V. Sweedler
Single-cell analysis by capillary electrophoresis
  • DOI:
    10.1007/s00216-002-1609-z
  • 发表时间:
    2003-01-01
  • 期刊:
  • 影响因子:
    3.800
  • 作者:
    Jeffrey N. Stuart;Jonathan V. Sweedler
  • 通讯作者:
    Jonathan V. Sweedler

Jonathan V. Sweedler的其他文献

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{{ truncateString('Jonathan V. Sweedler', 18)}}的其他基金

BI tims TOF fleX with MALDI-2 mass spectrometer
BI tims TOF flex 与 MALDI-2 质谱仪
  • 批准号:
    10630721
  • 财政年份:
    2023
  • 资助金额:
    $ 25万
  • 项目类别:
BRAIN Initiative: Integrated Multimodal Analysis of Cell and Circuit-Specific Processes in Hippocampal Function
BRAIN Initiative:海马功能中细胞和电路特异性过程的综合多模态分析
  • 批准号:
    9294862
  • 财政年份:
    2015
  • 资助金额:
    $ 25万
  • 项目类别:
Sampling and Separation Core
采样和分离核心
  • 批准号:
    7620681
  • 财政年份:
    2009
  • 资助金额:
    $ 25万
  • 项目类别:
Administrative Core
行政核心
  • 批准号:
    7620668
  • 财政年份:
    2009
  • 资助金额:
    $ 25万
  • 项目类别:
Protein Identification Core
蛋白质鉴定核心
  • 批准号:
    7620687
  • 财政年份:
    2009
  • 资助金额:
    $ 25万
  • 项目类别:
BioinformatJCS Core
生物信息JCS核心
  • 批准号:
    7620689
  • 财政年份:
    2009
  • 资助金额:
    $ 25万
  • 项目类别:
ADMINISTRATIVE CORE
行政核心
  • 批准号:
    7700098
  • 财政年份:
    2008
  • 资助金额:
    $ 25万
  • 项目类别:
The Neurometabolome of a Sensory Neuronal Network
感觉神经网络的神经代谢组
  • 批准号:
    7483119
  • 财政年份:
    2007
  • 资助金额:
    $ 25万
  • 项目类别:
The Neurometabolome of a Sensory Neuronal Network
感觉神经网络的神经代谢组
  • 批准号:
    7303676
  • 财政年份:
    2007
  • 资助金额:
    $ 25万
  • 项目类别:
The Neurometabolome of a Sensory Neuronal Network
感觉神经网络的神经代谢组
  • 批准号:
    7643343
  • 财政年份:
    2007
  • 资助金额:
    $ 25万
  • 项目类别:
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