Engineering encapsulation materials and methods to preserve organoids and biopsy material

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We are seeking a highly motivated student to undertake a multidisciplinary project to solve the problem of how to preserve 3D cell and tissues to enable hospitals and laboratories to undertake personalize medicine studies. Increasingly, it is appreciated that fresh clinical samples or 3D organoids are valuable resources that enable researchers to explore personalized treatments for diseases such as cancers. This project will work in an academic setting, but in collaboration with the biotech company Atelerix to explore their technology around cell encapsulation https://www.atelerix.co.uk/ and how this might be optimized for 3D organoids and biopsy material. Personalised medicine requires that laboratories and hospitals share samples of precious growing cells and living tissues, but the shipment can present problems, including expense, cell viability and preservation of original phenotype. This PhD project will explore the key biophysical parameters needed for optimal cell preservation to keep cells, organoids and tissues viable during transit to improve our capabilities to perform research, including around personalized medicine.