Biometrics

生物统计学核心的目标是为孢子研究人员提供接触到具有生物统计学方法及其应用于皮肤癌研究的经验的生物统计学家。生物识别核心工作人员将提供必要的研究方法方面的专业知识，以设计和实施针对特定目标1的严格研究研究。通过特定目标2，他们将提供支持有效数据库开发和数据库连接所需的信息学专业知识，以及为孢子研究实施样本设计以及描述性和推论统计分析所需的统计编程专业知识。作为具体目标3，他们将提供统计方法方面的专门知识 对研究假设的评估和孢子研究的研究目标所规定的统计模型的发展至关重要。最后，通过具体目标4，它们将对孢子数据库图书馆中存储的数据进行监督、维护和质量保证，方便与孢子有关的查询和使用。通过这些具体目标，生物识别核心将确保与孢子相关的研究将具有高质量的研究设计和统计分析计划，为统计推断提供坚实的基础。

The goal of the Biometrics Core is to provide SPORE investigators access biostatisticians who have experience with biostatistical methodology and their application to research studies in cancer of the skin. The Biometrics Core staff will provide expertise in research methodologies necessary to design and implement rigorous research studies in Specific Aim 1. Through Specific Aim 2 they will provide expertise in informatics necessary to support efficient database development and database linkage, as well as expertise in statistical programming necessary to implement sample designs and both descriptive and inferential statistical analyses for SPORE studies. By way of Specific Aim 3 they will provide expertise in statistical methodology critical in the evahtation of research hypotheses and in the development of statistical models specified by the research objectives of the SPORE studies. Lastly, through Specific Aim 4, they will provide oversight, maintenance and quality assurance for data stored in the SPORE Database Library, facilitating access to it for SPORE-related inquiries and uses. Through these specific aims the Biometrics Core will insure that SPORE-related studies will have high quality study designs and statistical analysis plans that will provide a solid foundation for statistical inferences.