CORE--Biostatistics Core D: U. of PA consortium

生物识别核心的目标是为研究人员提供该计划项目的访问权限 对生物统计学方法及其在黑色素瘤病因和进展研究中的应用有经验的生物统计学家。生物识别核心工作人员将提供必要的研究方法方面的专业知识，以设计和实施特定目标1的严格实验研究。通过特定目标2，他们将提供支持有效数据库开发和数据库链接所需的信息学专业知识，以及描述性和推断性统计分析所需的统计编程专业知识。作为具体目标3，它们将提供统计方法方面的专门知识，这些专门知识在评估研究假设和制定每个研究项目的研究目标所规定的统计模型方面至关重要。通过这些具体目标，生物识别核心将确保该项目将拥有高质量的研究设计和统计分析计划，为统计推断提供坚实的基础。

The goal of the Biometrics Core is to provide investigators in this program project access biostatisticians who have experience with biostatistical methodology and their application to research in melanoma etiology and progression. The Biometrics Core staff will provide expertise in research methodologies necessary to design and implement rigorous experimental studies in Specific Aim 1. Through Specific Aim 2 they will provide expertise in informatics necessary to support efficient database development and database linkage, as well as expertise in statistical programming necessary for both descriptive and inferential statistical analyses. By way of Specific Aim 3 they will provide expertise in statistical methodology critical in the evaluation of research hypotheses and in the development of statistical models specified by the research objectives of each of the research projects. Through these specific aims the Biometrics Core will insure that this program project will have high quality study designs and statistical analysis plans that will provide a solid foundation for statistical inference.