International Training Program in Environmental Immunoa*

环境免疫学国际培训项目*

• 批准号: 6875228
• 负责人: Jerold Alan Last
• 金额: $ 15万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-29 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6875228
• 关键词: International; Training; Program; Environmental; Immunoa

EXCEED THE SPACE PROVIDED. Data gaps exist in the assessment of human and environmental health largely due to the lack of ability to analyze large sample loads rapidly and cost effectively. Immunbassays can be used to measure toxic materials in the environment and for human monitoring because they are rapid, cost-effective, sensitive, specific and adaptable to laboratory or field situations. These assays can be used to measure potential exposure to these compounds in environmental samples such as soil and water, and in food. Ultimately, studies can be conducted which were previously cost prohibitive, thus providing a greater database from which to make informed decisions on human and environmental health. This project will provide simple and reliable methods for residue analysis and a trained University staff to educate technicians in how to use these methods in the field. The Faculty of Chemistry, University of the Republic (Uruguay), and its researchers has the necessary background to acquire this methodology and contribute to its further development. The University of California at Davis has an ongoing program in this area and represents an ideal training and technology transfer milieu to sponsor such a project. Thus, the project will build in the Departments of Immunology and Biochemistry of the University of the Republic the capability of developing immunoassays for monitoring environmental contamination and detection of chemical residues in food products according to the needs of the country. These assays are versatile, fast, sensitive, specific, and cost effective. The latter is particularly relevant for developing economies, such as that of Uruguay and other countries of the Mercosur, where the high cost of classical instrumental analysis is a strong limitation to its widespread use. We will encourage regional participation by other countries in the Mercosur, the southern portion of South America, in this Center. Such participants will include environmental toxicologists, public health professionals, and epidemiologists, all of whom will find benefits of ELISA technology for their disciplines. PERFORMANCE SITE ========================================Section End===========================================

超出所提供的空间。 在人类和环境健康评估方面存在数据缺口，主要是由于缺乏快速和具有成本效益地分析大量样本的能力。Immunobassays可用于测量环境中的有毒物质和人类监测，因为它们快速，具有成本效益，灵敏，特异性和适用于实验室或现场情况。这些检测可用于测量土壤和水等环境样品以及食品中这些化合物的潜在暴露。最终，可以进行以前费用高昂的研究，从而提供一个更大的数据库，据以就人类和环境健康作出知情的决定。 该项目将提供简单可靠的残留物分析方法和训练有素的大学工作人员，以教育技术人员如何在实地使用这些方法。共和国大学（乌拉圭）化学系及其研究人员具有获得这种方法并为其进一步发展做出贡献的必要背景。加州大学戴维斯分校在这一领域有一个正在进行的项目，并代表了一个理想的培训和技术转让环境，以赞助这样一个项目。因此，该项目将在共和国大学免疫学系和生物化学系建立开发免疫测定法的能力，以便根据国家的需要监测环境污染和检测食品中的化学残留物。这些测定是通用的、快速的、灵敏的、特异性的和成本有效的。后者对发展中经济体尤其重要，如乌拉圭和南方共同市场其他国家，在这些国家，传统仪器分析的高成本严重限制了其广泛使用。我们将鼓励南美洲南部南方共同市场的其他国家参加该中心的区域活动。这些参与者将包括环境毒理学家，公共卫生专业人员和流行病学家，他们都将发现ELISA技术对他们学科的好处。性能现场=