Extracellular cues compete with TCR signalling to alter lymphocyte polarity, fate and function.

点击翻译按钮获取中文摘要

Following an infection, our immune system generates a large and diverse repertoire of cells required to mount and regulate an appropriate immune response. The signals that control the different types of immune cells that develop, and how bacteria and viruses influence immune cell development, are not fully understood. This project will investigate the regulation of immune cell development, and how competing signals from infectious agents influence this process.