Programming physical and biological cues to promote vessel growth

对物理和生物信号进行编程以促进血管生长

• 批准号: FT230100249
• 负责人: A/Prof Khoon Lim
• 金额: $ 66.78万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2024
• 资助国家: 澳大利亚
• 起止时间: 2024-01-08 至 2028-01-07
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT230100249
• 关键词: Programming; physical; biological; cues; promote

This project aims to engineer new hydrogel-based biomaterials that allow spatio-temporal modulation of physical and biological cues to direct blood vessels growth, as well as compatible with advanced bioprinting platforms. It will generate new knowledge in biomaterials, biofabrication and advanced material processing. Expected outcomes include new knowledge in biomaterial-vascular interaction, novel vascular bioinks, cross-disciplinary, international collaboration and research training. This project will provide significant benefit to Australia's scholarly output and reputation, as well as long term benefits to biomedical, veterinary and cosmetic through new materials and cutting-edge manufacturing platforms.

该项目旨在设计新的基于水凝胶的生物材料，允许物理和生物线索的时空调节，以指导血管生长，并与先进的生物打印平台兼容。它将产生生物材料，生物织物和先进材料加工的新知识。预期成果包括生物材料-血管相互作用的新知识，新型血管生物墨水，跨学科，国际合作和研究培训。该项目将为澳大利亚的学术产出和声誉带来重大利益，并通过新材料和尖端制造平台为生物医学、兽医和化妆品带来长期利益。