Integrative Study of Vocal Development

声乐发展的综合研究

• 批准号: 7117580
• 负责人: DAVID S VICARIO
• 金额: $ 62.74万
• 依托单位: RUTGERS, THE STATE UNIV OF N.J.
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-12-08 至 2009-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7117580
• 关键词: animal developmental psychology; behavioral /social science research tag; data collection methodology /evaluation; developmental neurobiology; electrodes; electromyography; interdisciplinary collaboration; learning; psychoacoustics; psychomotor function; respiratory airway pressure; songbirds; vocalization

DESCRIPTION (provided by applicant): The proposed work will advance understanding of the neural mechanisms of sensory-motor learning by providing a quantitative description of the relationship between multiple physiological variables and vocal performance during development in a songbird, the zebra finch. Young male zebra finches learn their songs from adult models through a process of imitation that resembles human speech acquisition. Learned song, consists of a stereotyped sequence of distinct sounds produced by coordinated action of the two brain hemispheres, via right and left sound generators in the bird's syrinx (vocal organ), on patterned respiratory pressure pulses. Behavioral methods have been developed that trigger the vocal imitation process by presenting a model song, then measure the emerging structure of vocal output on a moment-to-moment basis. The bird rapidly transforms its limited, unstable vocal repertoire into a pattern of distinct syllable types defined by temporal and acoustic parameters - a process of differentiation and stabilization. This application proposes an interdisciplinary collaboration to study this learning process at the behavioral, articulatory, and brain levels in laboratories with expertise in physiological, behavioral and computational approaches to motol earning. Using the standardized behavioral paradigm, vocal output and physiological data will be recorded from different levels of the system at critical times during learning. The emerging structure of song will be elated to: 1) articulatory gestures recorded as respiratory pressure patterns and syringeal airflow; 2) premotor activity in subregions of vocal nucleus RA involved in respiratory vs. syringeal control; and 3) the role of synchronizing inputs to vocal nucleus HVC in song initiation and coordination. Quantitative analysis of the behavior and multi-level physiological data will yield a detailed account of how neural activity is structured into a learned temporal pattern during development and how multiple patterns, controlling different vocal effectors, combine to produce the song that is heard.

描述（由申请人提供）：拟议的工作将通过对多个生理变量与发育过程中多个生理变量之间的关系进行定量描述，以提高对感觉运动学习的神经机制的理解。年轻的男性斑马芬奇（Zebra Finches）通过类似于人类言语的模仿过程来从成人模型中学习他们的歌曲。学识渊博的歌曲，由两个大脑半球的协调作用产生的刻板印象序列，通过鸟的Syrinx（声音器官）中的左右声音发电机，在图案化的呼吸压力脉冲上通过左右声音发电机组成。已经开发了行为方法，该方法是通过呈现模型歌曲来触发声音模仿过程的，然后以瞬间为基础测量声音输出的新兴结构。鸟迅速将其有限的，不稳定的人声曲目转变为由时间和声学参数定义的不同音节类型的模式 - 分化和稳定的过程。该应用程序提出了跨学科的合作，以在实验室的行为，阐述和大脑水平上研究具有生理，行为和计算方法的专业知识的摩托车收入的专业知识。使用标准化的行为范式，在学习过程中，将从系统的不同级别记录声音输出和生理数据。歌曲的新兴结构将兴高采烈：1）记录为呼吸压力模式和注射气流的关节手势； 2）参与呼吸道与截骨对照的嗓音核的子区域的前活动； 3）在歌声核HVC中同步输入在歌曲启动和协调中的作用。对行为和多层次生理数据的定量分析将产生有关在开发过程中如何将神经活动构成到学习的时间模式的详细说明，以及如何控制不同的人声效应子，结合使用以产生听到的歌曲。