Mid-Career Investigator Award in Eating and Weight

此应用程序是在以患者为导向的研究K-24中期职业奖。候选人，卡洛斯M。Grilo博士，是耶鲁大学医学院精神病学副教授，他担任饮食失调项目主任。Grilo博士在饮食/体重紊乱方面有着以患者为导向的研究记录，在暴食症（BED）方面具有特定的专业知识。Grilo博士在患者研究方面有指导学员/教师的记录，并收到了三份少数民族培训补充材料。Grilo博士目前担任NIDDK R 01资助项目的PI，研究肥胖BED患者的不同治疗方法。该研究测试认知行为疗法（CBT），行为减肥（BWL）和序列CBT-BWL，是K-24期间的一个主要项目，并详细描述。Grilo博士目前担任Donaghue基金会资助的PI，该基金会资助测试肥胖/BED的不同指导自助行为治疗，以及美国心脏协会资助的一项随机安慰剂对照试验，该试验对肥胖/BED的CBT同时给予肥胖药物。Grilo博士之前作为PI获得了NIDDK R29资助，用于一项随机安慰剂对照比较试验，测试BED的心理和药理学治疗，以及NIMH R 03用于神经性贪食症的对照药理学试验。Grilo博士曾担任多个基金会和NIH赠款的共同研究员。预计未来将保持对研究的积极支持，特别是如果K-24被授予以确保临床管理职责的保护时间。 K-24将允许Grilo博士保持对饮食/体重紊乱的研究重点。为了增加他对解决这些重大公共卫生问题的贡献，K-24将使他能够进一步提高他作为调查员/导师的有效性。已找到国际公认的顾问。博士已经招募了强大的博士后研究员，并有能力指导他们和教师。资助项目为培养下一代饮食/体重紊乱临床研究人员提供了独特的资源

This application is for a K-24 Mid-Career Award in Patient-Oriented Research. The candidate, Carlos M. Grilo, Ph.D., is Associate Professor of Psychiatry at the Yale School of Medicine, where he serves as Director of the Eating Disorder Program. Dr. Grilo has an established record of patient-oriented research in eating/weight disorders, with specific expertise in binge eating disorder (BED). Dr. Grilo has a track record of mentoring trainees/faculty in patient research and has received three Minority-Training Supplements. Dr. Grilo currently serves as PI on a NIDDK R01 grant examining different treatments for obese BED patients. The study tests cognitive behavioral therapy (CBT), behavioral weight loss (BWL), and sequenced CBT-BWL, is one major project for the K-24 period, and is described in detail. Dr. Grilo currently serves as PI on a Donaghue Foundation grant testing different guided self-help behavioral treatments for obesity/BED and an American Heart Association grant for a randomized placebo-controlled trial of an obesity medication given concurrently with CBT for obesity/BED. Dr. Grilo previously received, as PI, a NIDDK R29 grant for a randomized placebo-controlled comparative trial testing psychological and pharmacological treatments for BED, and a NIMH R03 for a controlled pharmacologic trial for bulimia nervosa. Dr. Grilo has served as Co-Investigator on several Foundation and NIH grants. Maintaining active support for research in the future is anticipated, particularly if K-24 is awarded to ensure protected time from clinical-administrative duties. The K-24 will allow Dr. Grilo to maintain a research focus on eating/weight disorders. To increase his contributions addressing these major public health problems, the K-24 will allow him to further enhance his effectiveness as an investigator/mentor. Internationally recognized consultants have been secured. Dr. has recruited strong postdoctoral fellows and is well positioned to mentor them and faculty. Funded programs provide unique resources for training the next generation of clinical-researchers of eating/weight disorders