Restructuring Biomedical Sciences--Form and Function: Remodeling of Cooley Labor

描述（由申请人提供）：我们提出了一个在蒙大拿州州立大学（MSU）库利实验室的改造计划。Cooley实验室目前由四层楼和一个地下室组成，效率非常低，没有空气供应，集中冷却，真空或蒸馏/RO水。他们每年都被博兹曼消防局引用基础设施和过度使用的违规行为。在这项提案中，我们要求为一个完整的建筑改造计划提供资金，以创建一个新的最先进的设施，该设施将通过研究主题将来自不同部门的生物医学研究人员团结在唯一能够安全访问动物资源设施的建筑物中。密歇根州立大学的研究发展迅速，密歇根州立大学现在被列为卡内基I研究机构。然而，进一步的增长取决于有利于生物医学研究的研究空间的发展。现有的铲准备建设计划改造库利实验室，以产生一个可持续的，现代化的建筑，将动力新的，主题组织，研究集群在主机病原体相互作用，神经疾病，激光物理学的应用，生物医学问题。沿着结构和机械系统的全面检修，每一层都将根据这些主题需求进行定制。NIH在之前的项目中审查并批准了两层楼和相关基础设施（机械系统、结构），一直到施工文件。这个新项目将利用以前提交的设计，大大缩短开工时间。我们相信，2010年11月开工是可以实现的。该项目计划获得LEED银级认证，并已在USGBC注册。翻新现有设施，而不是建造新设施，符合良好的可持续做法，而且更具成本效益。仅设计和施工就将在蒙大拿州创造129个工作岗位，并将对现有的NIH资助的研究项目以及NCRR资助的基础设施赠款产生重大影响，如COBRE和INBRE项目。

DESCRIPTION (provided by applicant): We propose a program for the renovation of the Cooley Laboratories at Montana State University (MSU). Cooley laboratories currently consist of four floors and a basement that are highly inefficient, with no air supply, centralized cooling, vacuum, or distilled/RO water. They are annually cited by the Bozeman Fire Department for infrastructure and overuse violations. In this proposal, we are requesting funds for a full building renovation program to create a new state-of-the-art facility that will unite biomedical researchers from different departments by research themes in the only building with secure access to the animal resource facility. Research at MSU has grown rapidly, and MSU is now classified as a Carnegie I research institution. However, further growth depends upon the development of research space that is conducive to biomedical research. Shovel-ready construction plans exist to remodel the Cooley Laboratories to produce a sustainable, modern building that will power new, thematically organized, research clusters in host-pathogen interactions, neurological diseases, and application of laser physics to biomedical problems. Along with a complete overhaul of structure and mechanical systems, each floor will be customized to meet these thematic needs. NIH reviewed and approved two floors and associated infrastructure (mechanical systems, structure) in a previous project, all the way through construction documents. This new project will take advantage of the previous design submission and significantly shorten the time to the start of construction. We believe a November 2010 start date for construction is achievable. This project is planned to be LEED certified at a Silver level and has already been registered with USGBC. Renovating an existing facility, rather than building new, is in keeping with good sustainable practice, in addition to being more cost effective. Design and construction alone will account for 129 jobs in the state of Montana, and will have a significant impact on existing NIH-funded research programs as well as NCRR-funded infrastructure grants to MSU such as the COBRE and INBRE programs.