International Symposium on Genome-Wide Association Studies

全基因组关联研究国际研讨会

基本信息

  • 批准号:
    7193776
  • 负责人:
  • 金额:
    $ 3.75万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2006
  • 资助国家:
    美国
  • 起止时间:
    2006-08-14 至 2007-07-31
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): Recent years have seen great progress in the identifications and characterizations of millions of single nucleotide polymorphisms (SNPs) in the human genome, highlighted by the recent publication from the International HapMap Project. The knowledge on the SNPs coupled with the developments of various platforms for high-throughput, high quality genotyping have made genome-wide association studies within reach of human geneticists. However, significant challenges remain in the design, conduct, analysis, and interpretation of genome-wide association studies. Statistical genetics and epidemiological designs will play key roles to ensure the success of these studies. Therefore, a focused meeting on relevant methodological issues can stimulate novel ideas and exchange different views/approaches that can lead to more powerful designs and efficient analyses of genome-wide association studies. To address this need, we request funds to support an International Symposium on Genome-Wide Association Studies to facilitate discussions among leading scientists using genome-wide association strategies to identify genes underlying common diseases. The specific aims of this conference are to review the up-to-date knowledge of human population genetics from the International HapMap Project and other related efforts, to discuss design strategies for a genome-wide association study, to explore novel statistical and computational methods designed for genome-wide studies, to illustrate design and analysis issues through case studies, to introduce cutting-edge technologies that may prove indispensable for future studies, and to disseminate the knowledge and lessons learned from this conference to the general scientific community. A group of outstanding speakers have already committed to this meeting and they will play a leadership role at this conference. In addition, poster presentations selected from conference participants will provide ample opportunities for further exchanges and discussions among all conference attendees. The meeting materials will be made available to the public via several channels, such as published meeting report and conference web site, to further increase the impact of this conference.
描述(由申请人提供):近年来,在人类基因组中数百万个单核苷酸多态性(SNP)的鉴定和表征方面取得了巨大进展,国际人类基因组单体型图计划(International HapMap Project)最近的出版物突出了这一点。对SNP的了解,加上各种高通量、高质量基因分型平台的发展,使全基因组关联研究成为人类遗传学家力所能及的事情。然而,在全基因组关联研究的设计、实施、分析和解释方面仍然存在重大挑战。统计遗传学和流行病学设计将发挥关键作用,以确保这些研究的成功。因此,就相关的方法问题举行一次重点会议可以激发新的想法,并交流不同的观点/方法,从而为全基因组关联研究提供更强大的设计和更有效的分析。为了满足这一需求,我们要求资金支持全基因组关联研究国际研讨会,以促进领先的科学家使用全基因组关联策略来确定常见疾病的基因进行讨论。本次会议的具体目标是回顾国际HapMap项目和其他相关工作中人类群体遗传学的最新知识,讨论全基因组关联研究的设计策略,探索为全基因组研究设计的新统计和计算方法,通过案例研究说明设计和分析问题,介绍可能证明对今后的研究不可或缺的尖端技术,并向一般科学界传播这次会议的知识和经验教训。一批杰出的演讲者已经承诺参加这次会议,他们将在这次会议上发挥领导作用。此外,从与会者中选出的海报展示将为所有与会者提供进一步交流和讨论的充分机会。会议资料将通过发布的会议报告和会议网站等多种渠道向公众提供,以进一步扩大本次会议的影响。

项目成果

期刊论文数量(0)
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专利数量(0)

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HONGYU ZHAO其他文献

HONGYU ZHAO的其他文献

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{{ truncateString('HONGYU ZHAO', 18)}}的其他基金

Statistical Methods for Genetic Risk Predictions across Diverse Populations
不同人群遗传风险预测的统计方法
  • 批准号:
    10662188
  • 财政年份:
    2022
  • 资助金额:
    $ 3.75万
  • 项目类别:
Statistical Methods for Genetic Risk Predictions across Diverse Populations
不同人群遗传风险预测的统计方法
  • 批准号:
    10391800
  • 财政年份:
    2022
  • 资助金额:
    $ 3.75万
  • 项目类别:
Data Management Core
数据管理核心
  • 批准号:
    10698039
  • 财政年份:
    2022
  • 资助金额:
    $ 3.75万
  • 项目类别:
Statistical Methods for Genetic Risk Predictions across Diverse Populations
不同人群遗传风险预测的统计方法
  • 批准号:
    10731582
  • 财政年份:
    2022
  • 资助金额:
    $ 3.75万
  • 项目类别:
Statistical Methods for Analyzing Birth Defects Cohorts
分析出生缺陷队列的统计方法
  • 批准号:
    10372041
  • 财政年份:
    2021
  • 资助金额:
    $ 3.75万
  • 项目类别:
Analytical Core
分析核心
  • 批准号:
    9336550
  • 财政年份:
    2011
  • 资助金额:
    $ 3.75万
  • 项目类别:
Analytical Core
分析核心
  • 批准号:
    8555273
  • 财政年份:
    2011
  • 资助金额:
    $ 3.75万
  • 项目类别:
Lost-of-function variants in the 1000 genomes data set and implications to GWAS
1000 个基因组数据集中的功能丧失变异及其对 GWAS 的影响
  • 批准号:
    7882977
  • 财政年份:
    2010
  • 资助金额:
    $ 3.75万
  • 项目类别:
Lost-of-function variants in the 1000 genomes data set and implications to GWAS
1000 个基因组数据集中的功能丧失变异及其对 GWAS 的影响
  • 批准号:
    8141451
  • 财政年份:
    2010
  • 资助金额:
    $ 3.75万
  • 项目类别:
Theoretical Studies of Linkage Disequilibrium
连锁不平衡的理论研究
  • 批准号:
    6879911
  • 财政年份:
    2004
  • 资助金额:
    $ 3.75万
  • 项目类别:
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