International Symposium on Genome-Wide Association Studies

全基因组关联研究国际研讨会

• 批准号: 7193776
• 负责人: HONGYU ZHAO
• 金额: $ 3.75万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-08-14 至 2007-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7193776
• 关键词: genome; meeting /conference /symposium; travel

DESCRIPTION (provided by applicant): Recent years have seen great progress in the identifications and characterizations of millions of single nucleotide polymorphisms (SNPs) in the human genome, highlighted by the recent publication from the International HapMap Project. The knowledge on the SNPs coupled with the developments of various platforms for high-throughput, high quality genotyping have made genome-wide association studies within reach of human geneticists. However, significant challenges remain in the design, conduct, analysis, and interpretation of genome-wide association studies. Statistical genetics and epidemiological designs will play key roles to ensure the success of these studies. Therefore, a focused meeting on relevant methodological issues can stimulate novel ideas and exchange different views/approaches that can lead to more powerful designs and efficient analyses of genome-wide association studies. To address this need, we request funds to support an International Symposium on Genome-Wide Association Studies to facilitate discussions among leading scientists using genome-wide association strategies to identify genes underlying common diseases. The specific aims of this conference are to review the up-to-date knowledge of human population genetics from the International HapMap Project and other related efforts, to discuss design strategies for a genome-wide association study, to explore novel statistical and computational methods designed for genome-wide studies, to illustrate design and analysis issues through case studies, to introduce cutting-edge technologies that may prove indispensable for future studies, and to disseminate the knowledge and lessons learned from this conference to the general scientific community. A group of outstanding speakers have already committed to this meeting and they will play a leadership role at this conference. In addition, poster presentations selected from conference participants will provide ample opportunities for further exchanges and discussions among all conference attendees. The meeting materials will be made available to the public via several channels, such as published meeting report and conference web site, to further increase the impact of this conference.

描述（由申请人提供）：近年来，在人类基因组中数百万个单核苷酸多态性（SNP）的鉴定和特征方面取得了长足的进步，这是由国际Hapmap项目的最新出版物强调的。关于SNP的知识以及用于高通量，高质量基因分型的各种平台的发展，使全基因组的关联研究在人类遗传学家范围内。但是，在全基因组关联研究的设计，进行，分析和解释中仍然存在重大挑战。统计遗传学和流行病学设计将发挥关键作用，以确保这些研究的成功。因此，针对相关方法论问题的重点会议可以刺激新颖的思想，并交换不同的观点/方法，这可以导致更强大的设计和对全基因组关联研究的有效分析。为了满足这一需求，我们要求资金支持全基因组关联研究的国际研讨会，以促进主要科学家之间使用全基因组关联策略来识别基因基因的讨论。这次会议的具体目的是审查国际HAPMAP项目和其他相关工作的人口遗传学的最新知识，讨论针对全基因组关联研究的设计策略，以探索为全基因组研究设计的新颖统计和计算方法，以通过案例研究来介绍案例研究的设计和分析，以介绍详细的研究和详细的研究，从而介绍了详尽的研究，以介绍这些研究的秘密研究，从而使未来的研究构成了索引，从而涉及索引，从而涉及索引，从而涉及索引，从而涉及索引，从而涉及研究和分析问题，从而介绍了构成范围的研究，从而介绍了涉及的研究和分析问题。科学界。一群杰出的演讲者已经致力于这次会议，他们将在这次会议上扮演领导角色。此外，会议参与者选择的海报演示将为所有会议参与者之间的进一步交流和讨论提供足够的机会。会议材料将通过多个渠道（例如发布的会议报告和会议网站）向公众提供，以进一步增加该会议的影响。