Scientific Meeting: Mechanisms of Cell Death

科学会议：细胞死亡机制

• 批准号: 7169798
• 负责人: ZAHRA ZAKERI
• 金额: $ 1.3万
• 依托单位: QUEENS COLLEGE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-06-01 至 2007-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7169798
• 关键词: aging; apoptosis; cell cycle; cell death; cellular oncology; immunopathology; meeting /conference /symposium; travel

DESCRIPTION (provided by applicant): We request funds to support the 6th Biannual Conference on Cell Death, to be held at Angra dos Reis, Brazil June 02-05 2006. The theme of the conference will be "Cell Cycle and Cell Death in Aging, Cancer and Immune Related Diseases". Programmed cell death and apoptosis are important in several disciplines, including immunology, oncology, neurology, infectious diseases, cardiac infarct and stroke, reproductive biology, teratology, and environmental medicine. A major goal of our society is to maintain a fruitful and synergistic dialog among these disciplines. In this conference we will focus on cell cycle alterations and the mechanisms of cell death induction and survival. Our meeting-associated training course will introduce the main recent findings on Cell Cycle, Cell Death and Aging. We will address and correlate the mechanisms of cell cycle and cell death pathways with age-related pathologies, such as neurodegenerative and cardiovascular diseases, cell cycle and cancer. We will maintain focus on the potential of these findings for therapy and the relationship of laboratory to clinical data. Sensitivity to apoptosis is frequently tightly linked to both cell cycle and the presence or absence of growth factors, both of which vary strongly with age; and the ability of cells to die only at appropriate physiological times is a major factor of both proliferative and degenerative diseases of aging. Our record of equality in ethnic and gender distribution among speakers is excellent (estimated 1/3 this year), as is our accommodation for specific needs. We will take direct steps to continue and enhance this record. We also have an excellent record of supporting and featuring upcoming junior scientists at these meetings. This conference will be a unique opportunity to gather scientists from the USA, Europe and South America. We have published 2 Annals of the New York Academy of Sciences from these meetings, and the last meeting served as a basis for the organization of the second edition of When Cells Die (Wiley-Liss). We expect that this meeting will lead to further publications. We are currently negotiating publication arrangements. NIH funds will be used to support speakers and facilities. Future meetings in France and China are planned.

描述（由申请人提供）：我们请求资金支持第六届细胞死亡半年会议，将于2006年6月2日至5日在巴西安格拉杜斯雷斯举行。会议的主题是“衰老、癌症和免疫相关疾病中的细胞周期和细胞死亡”。程序性细胞死亡和细胞凋亡在免疫学、肿瘤学、神经学、感染性疾病、心肌梗死和中风、生殖生物学、畸形学和环境医学等多个学科中都很重要。我们社会的一个主要目标是保持这些学科之间富有成效的和协同的对话。在这次会议上，我们将集中在细胞周期的改变和细胞死亡诱导和生存的机制。我们的会议相关培训课程将介绍细胞周期，细胞死亡和衰老的主要最新发现。我们将解决和相关的细胞周期和细胞死亡途径与年龄相关的病理机制，如神经退行性疾病和心血管疾病，细胞周期和癌症。我们将继续关注这些发现的治疗潜力以及实验室与临床数据的关系。对细胞凋亡的敏感性通常与细胞周期和生长因子的存在或不存在紧密相关，这两者都随年龄而强烈变化;细胞仅在适当的生理时间死亡的能力是衰老的增殖性和退行性疾病的主要因素。我们在发言者的种族和性别分布方面的平等记录非常好（今年估计为1/3），我们满足特定需求的情况也是如此。我们将采取直接措施，继续保持和加强这一记录。我们在这些会议上也有支持和介绍即将到来的年轻科学家的出色记录。这次会议将是一个独特的机会，聚集来自美国，欧洲和南美洲的科学家。我们从这些会议中出版了2份纽约科学院年鉴，最后一次会议作为组织第二版《细胞死亡时》（Wiley-Liss）的基础。我们期望这次会议将导致更多的出版物。我们目前正在协商出版安排。NIH的资金将用于支持演讲者和设施。计划今后在法国和中国举行会议。