Core--Data Coordination and Statistics

数据协调和统计核心（DCSC）的主要目标是为现场程序和数据管理提供连贯一致的方法，并在所有项目和核心之间共享统计方法。通过标准化协议和集中数据管理，我们不仅确保数据完整性并实现个人研究目标，而且还促进了项目和核心研究者之间的项目间科学合作。数据管理和协调部分将为项目和核心数据的管理、质量控制、质量保证、储存和访问提供集中的专门知识和资源。DCSC将提供集中的数据跟踪、处理、质量保证程序， 文件管理。最后，DCSC将确保项目研究者能够通过一个具有定期备份和存档功能的集中式共享访问研究数据库及时访问数据。环境统计部分将作为一个集中资源，用于了解和实施项目所需的统计方法，包括分析面板数据和案例交叉研究，以及非参数平滑方面的专门知识，包括在混合模型、重复测量、结构方程模型和风险评估方面的专门知识。

The primary goal of the Data Coordination and Statistical Core (DCSC) is to provide a coherent and consistent approach to field procedures and data management, with sharing of statistical methodology across all Projects and Cores. By standardizing protocols and centralizing data management, we not only insure data integrity and realize individual study goals, but we also facilitate inter-project scientific collaboration amongst Project and Core investigators. The Data Management and Coordination Component will provide centralized expertise and resources for management, quality control, quality assurance, storage and access to Project and Core data. The DCSC will provide centralized data tracking, processing, quality assurance procedures and documentation management. Finally the DCSC will ensure that data are accessible to Program investigators in a timely fashion, through a centralized, shared-access study database with regular back-up and archiving. The Environmental Statistics Component will serve as a centralized resource for understanding and implementing the statistical methods needed for the projects, including analysis of panel data and case-crossover studies, as well as expertise in nonparametric smoothing, including within the context of mixed models, repeated measures, structural equation models, and risk assessment.