HSPH-NIEHS Center for Environmental Health

HSPH-NIEHS 环境健康中心

基本信息

批准号：
8245648
负责人：
Douglas W Dockery
金额：
$ 178.88万
依托单位：
HARVARD SCHOOL OF PUBLIC HEALTH
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
起止时间：
1997-04-01 至 2014-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8245648
关键词：
Address Affect Air Animals Asthma Attention deficit hyperactivity disorder Autistic Disorder Basic Science Behavior Biological Biology Birth Boston Breathing British Case-Control Studies Cause of Death Cells Cellular biology Cessation of life Child health care Chronic Chronic lung disease Clinical Cohort Studies Collaborations Community Health Education Community Outreach Complex Control Groups Core Facility Country Coupled Developed Countries Developing Countries Development Diagnosis Disease Economic Conditions Economics Educational process of instructing Environment Environmental Epidemiology Environmental Exposure Environmental Health Environmental Risk Factor Epidemiology Etiology Exposure to Family Financial Support Fostering Gene Expression Genes Genetic Genetic Polymorphism Genetic Predisposition to Disease Genome Genomics Genotype Grant Health Health Care Costs Human Impairment Individual Infectious Agent Interdisciplinary Study International Knowledge Leadership Life Link Malignant Neoplasms Measures Metals Methodology Methods Modality Modeling Molecular Biology Monozygotic twins Morbidity - disease rate National Institute of Environmental Health Sciences Nature Neurocognitive Obesity Occupational Outcome Particulate Matter Pathology Patients Persons Pharmacology Phase Physiology Pilot Projects Population Predisposition Prevalence Prevention Problem behavior Productivity Public Health Quality of life Reader Research Research Personnel Research Training Role Science Science of genetics Site Social Conditions Societies Speed Staging Surface Time Toxic Environmental Substances Toxicant exposure Training Work case control cohort design developmental disease disability fetal gene environment interaction genetic analysis genetic epidemiology genetic risk factor holistic approach human DNA innovation insight interest knowledge base longitudinal design multidisciplinary new technology organizational structure particle pollutant programs prospective response social statistics toxicant

项目摘要

DESCRIPTION (provided by applicant) : This amended application is designed to respond as completely as possible to concerns of the site visitors and of subsequent review groups. Accordingly, eight disciplinary Research Cores have been replaced by three multidisciplinary, integrated Research Cores. Facility Cores have been strengthened. The requirements and benefits of Center membership have been clarified. Leadership issues have been addressed. In toto, this program has been refocused and energized by these structural changes. Our Center fosters active collaborations among three Research Cores: 1) Metals, 2) Urban and Occupational Particles, and 3) Organic Pollutants. The work of the Research Cores is greatly enhanced by three Facility Cores: 1) Biological Analyses, 2) Exposures and Environmental Analyses, and 3) Environmental Statistics. Finally, the investigators' ability to make their research and knowledge available to the public is greatly enhanced by the Community Outreach and Education Program (COEP). Other Center activities, such as pilot projects, new investigators, and program enrichment are catalytic mechanisms to achieve integration, interaction, productive, and innovative science. The objectives of this NIEHS Center are to generate new knowledge relating to the physiology, pharmacology, pathology, cell biology, molecular biology, genetics, and epidemiology of environmental disease, and to apply this knowledge to new modalities of prevention, diagnosis, and therapy. The investigators achieve these objectives through a variety of approaches, which range from studies of molecules and cells to those of whole animals and human populations. Through the organizational structure and financial support provided by the NIEHS Center Grant, the investigators' will increase the impact of their research and teaching in environmental health. In toto, the Harvard NIEHS Center for Environmental Health continues to be a major focal point for environmental research and training in Boston. The NIEHS Center mechanism enhances connections and makes the Harvard NIEHS Center part of a national and international network.

描述（由申请人提供）：该修订的申请旨在尽可能完全响应现场访问者和随后的审核小组的顾虑。因此，八个纪律研究核心已被三个多学科的综合研究核心所取代。设施核心已得到加强。中心会员资格的要求和好处已被阐明。领导问题已经解决。在Toto中，这些程序已被这些结构变化重新集中和充满活力。我们的中心促进了三个研究核心之间的积极合作：1）金属，2）城市和职业颗粒，以及3）有机污染物。研究核心的工作通过三个设施核心大大增强：1）生物学分析，2）暴露和环境分析以及3）环境统计。最后，社区外展和教育计划（COEP）大大提高了调查人员使研究和知识向公众提供的能力。其他中心活动，例如试点项目，新的研究人员和计划丰富，是实现整合，互动，生产力和创新科学的催化机制。该NIEHS中心的目标旨在产生与生理学，药理学，病理学，细胞生物学，分子生物学，遗传学和环境疾病流行病学有关的新知识，并将这些知识应用于预防，诊断和治疗的新方式。研究人员通过多种方法实现这些目标，从分子和细胞的研究到整个动物和人类种群的目标。通过NIEHS中心赠款提供的组织结构和财政支持，调查人员将增加其研究和教学对环境健康的影响。在Toto，哈佛NIEHS环境卫生中心仍然是波士顿环境研究和培训的主要焦点。 NIEHS中心机制增强了联系，并使哈佛NIEHS中心成为国家和国际网络的一部分。