Development of a Mind-Body Center at NYUSOM

NYUSOM 身心中心的发展

基本信息

批准号：
7119545
负责人：
PAULINE F MCHUGH
金额：
$ 49.51万
依托单位：
NEW YORK UNIVERSITY SCHOOL OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
2004
资助国家：
美国
起止时间：
2004-09-15 至 2008-08-31
项目状态：
已结题

项目摘要

DESCRIPTION (provided by applicant): Stress is a complex medical problem in which psychological, social, cultural, and physiological factors all can interact in the development of illness. Stress-related health problems are endemic, and can take on any number of medical or psychiatric forms. This grant proposal describes a plan for the development of a new multidisciplinary mind-body center at NYU dedicated to basic, clinical, and translational research in stress and health. The unifying scientific themes of this center focus on the interactions of psychosocial stress, limbic brain, the neuroendocrine stress response (particularly the hypothalamic-pituitary-adrenal axis and the sympathoadrenergic system) and the downstream effects of the stress response on physical and mental functioning. Other themes of this center include understanding the maladaptive stress-induced behaviors that worsen stress and health, as well as coping mechanisms and other protective factors that ameliorate the health effects of stress. The goal of this center is to build an intellectual environment in which program scientists from a variety of fields can meet for the free exchange of ideas and to develop standardized batteries of assessments for use in interdisciplinary research projects. An Administrative Core would organize center activities and funds, and would be responsible for data management. A Research Core would bring together program scientists and resources, and would be governed by committee. Pilot projects would serve as the starting point for the development of central standardized resources, including clinical protocols, basic science methods, and neuroimaging protocols. A Training & Development Core would provide cross-disciplinary training for group members and a forum for young researchers and clinicians to learn about research in stress and health, and to interact closely with senior investigators. Educational goals of the center include community and trainee outreach and annual conferences. The long-term vision for the proposed center is one in which ongoing interdisciplinary longitudinal studies of stress and health would coexist with individual research projects that utilize the same shared resources. Such an infrastructure would promote greater knowledge among individual researchers and would enrich the field of stress research by providing a regular forum for the discussion of research issues and plans for future projects. This infrastructure also would improve research cost efficiency by preventing study duplication, providing a centralized shared resources, and having an intrinsic system of checks and balances within the governing committee.

描述（由申请人提供）：压力是一个复杂的医学问题，心理，社会，文化和生理因素都可以在疾病的发展中相互作用。与压力有关的健康问题是地方性的，可以采取任何数量的医学或精神病形式。该赠款提案描述了一项计划，以制定纽约大学新的多学科思维体中心，该中心致力于压力和健康方面的基本，临床和转化研究。该中心的统一科学主题集中于社会心理压力，边缘大脑，神经内分泌压力反应的相互作用（尤其是下丘脑 - 垂体 - 肾上腺轴和交感神经能力系统）以及应激反应对身体和精神功能的下游影响。该中心的其他主题包括了解压力和健康的不良压力引起的行为，以及应对机制和其他保护因素，这些因素可以改善压力的健康影响。该中心的目的是建立一个智力环境，其中各个领域的计划科学家可以开放思想的自由交流，并开发标准化的评估电池，以用于跨学科研究项目。行政核心将组织中心活动和资金，并负责数据管理。研究核心将汇集计划的科学家和资源，并由委员会统治。试点项目将成为开发中央标准化资源的起点，包括临床方案，基础科学方法和神经影像学方案。培训与发展核心将为小组成员和一个论坛提供跨学科培训，以供年轻的研究人员和临床医生学习压力和健康研究，并与高级研究人员进行紧密互动。该中心的教育目标包括社区和学员的外展和年度会议。拟议中心的长期愿景是，持续的压力和健康跨学科纵向研究将与利用相同共享资源的个人研究项目共存。这样的基础设施将通过提供一个定期讨论研究问题和未来项目计划的论坛来促进个人研究人员之间的更多知识，并将丰富压力研究领域。该基础设施还将通过防止研究重复，提供集中的共享资源，并在理事委员会内建立固有的制衡系统来提高研究成本效率。