DEVELOPMENT OF A MIND-BODY CENTER AT NYU

纽约大学身心中心的发展

• 批准号: 7605772
• 负责人: PAULINE F MCHUGH
• 金额: $ 0.55万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7605772
• 关键词: Adenosine; Adrenergic Receptor; Animal Model; Bisexual; Blood; Blood Pressure; Blood Tests; Brain; Clinical; Cognitive; Computer Retrieval of Information on Scientific Projects Database; Data; Databases; Development; Discipline; Electrocardiogram; Environment; Equilibrium; Funding; Future; Gays; Goals; Grant; Health; Health Services Research; Immunity; Individual; Institution; Interdisciplinary Study; Laboratories; Longitudinal Studies; Magnetic Resonance Imaging; Measurement; Medical; Memory; Methamphetamine; Outcome; Patients; Personality; Physiologic pulse; Pilot Projects; Population; Protocols documentation; Psychological Stress; Pulse taking; Questionnaires; Recording of previous events; Recruitment Activity; Research; Research Personnel; Resource Sharing; Resources; Role; Saliva; Sampling; Scientist; Source; Standards of Weights and Measures; Stress; Survivors; Symptoms; System; Time; Torture; Translational Research; Trauma; United States National Institutes of Health; Urine; Vision; War; allostatic load; body-mind; computerized; coping; cost; frontal lobe function; human subject; improved; medical schools; men; neuropsychological; prevent; programs; receptor; social cognition; volunteer

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This protocol concerns the inclusion of medical, psychiatric, and neuropsychological data from human subjects into a centralized database, for use by a group of investigators who are developing the new Mind-Body Center at NYU School of Medicine. This database will be made up of information about study volunteers either recruited specifically for the database or recruited after participating in one of the pilot studies that will be sponsored by this new center. Pilot studies will seek approval separately from this application. The NYU Mind-Body Center is a multidisciplinary research center dedicated to basic, clinical, and translational research of the interactions of stress and health. Consistent with our understanding of stress as a medical problem requiring research input from many disciplines, the goal of this center is to include program scientists from a variety of fields, in order to construct an intellectual environment for the free exchange of ideas. In the long-term vision for the center, ongoing interdisciplinary longitudinal studies of stress and health with shared central resources co-exist with individual projects, thus providing a regular forum for the discussion of research issues and plans for future projects, improving research cost efficiency by preventing study duplication, providing shared resources, and having an intrinsic system of checks and balances within the governing research services committee. The database mentioned here is one of the primary shared resources of this new center. Information collected from study volunteers include: full medical and psychiatric histories; a limited physical exam consisting of an EKG, pulse, and blood pressure measurements; standard laboratory tests of blood and urine; psychiatric symptom screens; a standard clinical MRI study of the brain; and standard computerized cognitive measurements of memory and frontal lobe function. Questionnaires about stress exposure, personality, and coping styles will also be administered. Blood and saliva samples will be collected and stored for further studies. Volunteers participating in this study will have the option of agreeing to be contacted by the center's Program Scientists for future studies. Subjects will not be obligated to participate in any further studies, although the data they give may be used by any of the center's scientists at future times. Proposed pilot studies include the following: Pilot Study #1: The Formation of a Central Database Evaluating Allostatic Load, Stress/Trauma, and Medical Outcomes in Diverse Patient Populations Pilot Study #2: Stress, Methamphetamine Abuse and Social Cognitions among Gay/Bisexual Men Pilot Study #3: Animal Models of Stress: Stress and Brain alpha-Adrenoceptor Function Pilot Study #4: Psychological stress-induced alteration in immunity: the role of adenosine and its receptors. Pilot Study #5: Coping Strategies among Survivors of Torture and War-related Trauma

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 该协议涉及将人类受试者的医学，精神病学和神经心理学数据纳入集中式数据库，以供一群正在开发纽约大学医学学院新思维中心的研究者。 该数据库将由有关专门为数据库招募的研究志愿者提供的信息组成，或者在参加该新中心赞助的一项试点研究后被招募。 试点研究将与此应用程序分开寻求批准。 纽约大学思维体中心是一个多学科研究中心，致力于对压力与健康相互作用的基本，临床和翻译研究。 与我们对压力的理解是一个医学问题，需要许多学科的研究意见，该中心的目的是包括各个领域的计划科学家，以构建一个知识环境以自由交流思想。 在对该中心的长期愿景中，正在进行的跨学科纵向研究压力和健康与共享的中央资源与单个项目共存，从而为讨论研究问题和未来项目的计划提供了定期论坛，通过预防研究重复，提供共享资源以及在副研究服务委员会内提供了内在的检查系统和衡量委员会，从而提高研究成本效率。 这里提到的数据库是该新中心的主要共享资源之一。 从研究志愿者那里收集的信息包括：完整的医学和精神病学历史；有限的身体检查有限，包括心电图，脉搏和血压测量；标准的血液和尿液测试；精神病症状筛查；大脑的标准临床MRI研究；和标准的计算机认知测量值和额叶功能。 还将管理有关压力暴露，个性和应对方式的问卷。 血液和唾液样品将被收集并存储以进行进一步研究。 参加这项研究的志愿者将可以选择同意该中心的计划科学家与未来的研究联系。 尽管中心的科学家可以在未来的任何时候使用，但他们提供的数据可能会使用。 拟议的试点研究包括以下内容： 试点研究＃1：在多种患者人群中评估同性载荷，压力/创伤和医疗结果的中央数据库的形成 试点研究＃2：同性恋者/双性恋男人的压力，甲基苯丙胺滥用和社会认知 试点研究＃3：压力的动物模型：压力和脑α-肾上腺素受体功能 试点研究＃4：心理压力引起的免疫改变：腺苷及其受体的作用。 试点研究＃5：酷刑和与战争相关的创伤幸存者的应对策略