Development of novel diagnostics for stroke

开发新的中风诊断方法

• 批准号: 2717546
• 金额: --
• 依托单位: University of Warwick
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2717546
• 关键词: Development; novel; diagnostics; stroke

Novel biotechnology approaches can radically improve outcomes for patients through the development of minimally invasive, highly sensitive diagnostic tools that can readily be used at the point-of-care and in emergency situations. This academic/biotech collaborative project brings together research expertise in the biological response to stroke with manufacturing excellence in the development of biosensors. Utilising relevant models of stroke, the project will: identify biomarkers of stroke; develop and optimise technical solutions for the detection of these biomarkers, and, using these approaches, will chart the profile of release of the biomarkers after stroke. This project thus offers the successful candidate deep insight into the neurobiology of the brain and its response to stroke, training in experimental models of stroke, exposure to an advanced commercial biotechnology environment, and the prospect of identifying informative biomarkers and developing commercially viable diagnostic tools.

新的生物技术方法可以通过开发可在护理点和紧急情况下随时使用的微创、高灵敏度诊断工具，从根本上改善患者的预后。这个学术/生物技术合作项目汇集了中风生物反应的研究专业知识和生物传感器开发的卓越制造。利用中风的相关模型，该项目将：确定中风的生物标志物;开发和优化检测这些生物标志物的技术解决方案，并使用这些方法，绘制中风后生物标志物释放的概况。因此，该项目为成功的候选人提供了对大脑神经生物学及其对中风的反应的深入了解，中风实验模型的培训，暴露于先进的商业生物技术环境，以及识别信息生物标志物和开发商业上可行的诊断工具的前景。