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Pharmacokinetics of Pulse-Sprayed TPA

Pharmacokinetics of Pulse-Sprayed TPA
脉冲喷雾 TPA 的药代动力学
批准号:
7004838
负责人:
mcdonald k horne
金额:
$0.0万
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依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
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英文摘要
For several years we have been treating deep vein thrombosis with recombinant tissue plasminogen activator that is injected directly into the clots. We have now collected blood samples before and at several time points following the treatment to determine how long the drug has a systemic effect. We found that it only circulates in an active form for 1 - 2 hours after injection and then becomes inhibited by a rise in plasminogen activator inhibitor-1. This work has now been published.
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Evaluation Of Hypercoagulability In Patients With Major
  • 批准号:
    6825561
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    --
  • 负责人:
    mcdonald k horne
  • 依托单位:
Pharmacokinetics of Pulse-Sprayed TPA
  • 批准号:
    6825587
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    --
  • 负责人:
    mcdonald k horne
  • 依托单位:
Lab Tests for Heparin Induced Thrombocytopenia
  • 批准号:
    6825589
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    --
  • 负责人:
    mcdonald k horne
  • 依托单位:
Interaction Of Plasminogen With Human Platelets
  • 批准号:
    6663619
  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
    --
  • 负责人:
    mcdonald k horne
  • 依托单位:
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