Fighting epidermal skin cancers by targeting epidermal clones that accumulate mutations

通过靶向积累突变的表皮克隆来对抗表皮皮肤癌

• 批准号: nhmrc : GNT1145350
• 负责人: A/Pr Kiarash Khosrotehrani
• 金额: $ 114.94万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/fighting-epidermal-skin-accumulate-mutations/1348687
• 关键词: Fighting; epidermal; skin; cancers; targeting

Common skin cancers such as basal and squamous cell carcinomas (BCC and SCC) are by far the most frequent cancer worldwide and require over a million interventions per year in Australia. This project will identify the skin cells that are most susceptible to give rise to cancer if excessively exposed to the sun and explores ways to prevent cancer formation. This will inform on new strategies to prevent new skin cancer development.

常见的皮肤癌，如基底细胞癌和鳞状细胞癌（BCC和SCC）是迄今为止全球最常见的癌症，在澳大利亚每年需要超过一百万次干预。该项目将确定如果过度暴露在阳光下最容易引起癌症的皮肤细胞，并探索预防癌症形成的方法。这将为预防新皮肤癌发展的新策略提供信息。