Stem cell treatment for neonatal hypoxic ischaemic encephalopathy

干细胞治疗新生儿缺氧缺血性脑病

• 批准号: nhmrc : GNT1145450
• 负责人: A/Pr Kiarash Khosrotehrani
• 金额: $ 95.42万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/stem-cell-treatment-ischaemic-encephalopathy/1348694
• 关键词: Stem; cell; treatment; neonatal; hypoxic

Hypoxic-ischaemic encephalopathy occurs when the fetus receives inadequate oxygen in labour and many babies die or have brain damage. Stem cell therapy might save these babies from brain damage but there are many unknowns, such as which stem cells to use and how many. Through our skills in stem cells and measuring the rescued brain following injury, we will determine the necessary details for the most effective stem cell therapy to be ready to immediately test the treatment in a RCT in babies.

缺氧缺血性脑病发生在胎儿在分娩时缺氧时，许多婴儿死亡或有脑损伤。干细胞疗法可能会使这些婴儿免于脑损伤，但仍有许多未知因素，例如使用哪种干细胞以及使用多少干细胞。通过我们在干细胞方面的技能和对受伤后获救大脑的测量，我们将确定最有效的干细胞治疗的必要细节，以便在婴儿的随机对照试验中立即测试这种治疗。