Systems analysis of epidermal biology and cancer

表皮生物学和癌症的系统分析

• 批准号: nhmrc : GNT1082438
• 负责人: A/Pr Kiarash Khosrotehrani
• 金额: $ 125.38万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/systems-analysis-epidermal-biology-cancer/1345462
• 关键词: Systems; analysis; epidermal; biology; cancer

Squamous cell carcinoma of the skin is extremely common in Australia, resulting in disfiguring surgeries and deaths. Although cumulative sun exposure is important, some people are very susceptible, and we do not know why. This project hinges on the notion that skin cancer is a complex (many genes involved). We will utilize novel systems to harness this complexity to understand why some people are resistant and others very susceptible so as to design appropriate control measures and treatments.

皮肤鳞状细胞癌在澳大利亚非常常见，导致毁容手术和死亡。虽然累积的阳光照射很重要，但有些人非常容易受到影响，我们不知道为什么。这个项目的关键在于皮肤癌是一个复杂的概念（涉及许多基因）。我们将利用新的系统来利用这种复杂性，以了解为什么有些人具有耐药性，而另一些人非常敏感，以便设计适当的控制措施和治疗方法。