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Implementation of new 3D printed & advanced materials sensors for the bio analysis of dysphagia patients

Implementation of new 3D printed & advanced materials sensors for the bio analysis of dysphagia patients
实施新的3D打印
批准号:
2726166
负责人:
金额:
$0.0万
依托单位:
依托单位国家:
英国
项目类别:
Studentship
财政年份:
2022
资助国家:
英国
项目状态:
未结题
起止时间:
2022 至 --

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中文摘要
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英文摘要
Dysphagia is difficulty in swallowing. Although classified under "symptoms and signs" in ICD-10, in some contexts it is classified as a condition in its own right. It may be a sensation that suggests difficulty in the passage of solids or liquids from the mouth to the stomach, a lack of pharyngeal sensation or various other inadequacies of the swallowing mechanism. Dysphagia is a common secondary symptom of many diseases, for example, 50-75% of stroke patients suffer from Dysphagia. In 2018, Stroke of the Nation, stated over 100,000 people suffer stroke yearly in the UK, with 1.2 million stroke survivors. This equates to 600,000- 850,000 dysphagia sufferers within the stroke cohort alone (pre-SARS-CoV-2/COVID 19). Viscgo estimates 187,000 UK yearly aspirational pneumonia cases. Adverse outcomes lead to avoidable illness and prolonged hospitalisation. Incorrect intervention can impede treatment, increase cost, length of hospitalisation stays and increase risk of severity or death.Current state of art to treat dysphagia include video fluoroscopy, a fiberoptic endoscopic evaluation of swallowing (FEES) test and diagnostic tools which are prohibitively expensive, inconclusive, and impractical to use regularly. Descriptor categorisations, which are inaccurate, time-consuming and require multiple components and dexterity (which also leads to user conflict), are intended for training only and are not recorded.Currently, speech and language therapists perform specific assessments when treating patients suffering from dysphagia. These assessments include recording and evaluation using tests (video fluoroscopy and FEES) that are then evaluated via a process of multiple pathways. These pathways are determined from results which are purely observational and therefore open to interpretation and as such are subjective. There are hundreds of different tests (and combination of these tests) currently used. Examples of tests include the turning of the patients head to one side and observing the swallowing function in the throat (eg speed of swallow, coughing or spluttering) or the nurse applying a compression against the patients throat and observing them whilst they swallow. These tests are all crude and without reliable outcome measures.Viscgo has developed a step change approach to dysphagia. They have developed a sensor capability that can be placed on the patients throat in order to quantitively and reproducibly assess the patients swallowing function. This PhD project will further develop this wearable technology by investigating the use of smart piezoelectric sensor arrays that have the capability to gain functional data to assist in the determination of physiology against food and drink related dependencies. In addition, this throat sensor technology will have the potential to also actively stimulate local and specific muscles involved in swallowing, thus offering a potential treatment to rehabilitate patients suffering from stroke induced dysphagia.
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