Core--Neuroimaging and neuroanatomy

核心--神经影像与神经解剖学

• 批准号: 7085557
• 负责人: ANTONIO R DAMASIO
• 金额: $ 12.81万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7085557
• 关键词: bioimaging /biomedical imaging; biomedical facility; brain imaging /visualization /scanning; brain injury; brain mapping; clinical research; human subject; magnetic resonance imaging; neuroanatomy

The Core project is the central resource of the Program. It encompasses five Core Units, which carry out the following operations: (a) Patient Registry, which regards the identification, screening and induction of subjects into the Registry, and the central Database and data management for neuroanatomical and neuropsychological data; (b) performance of neuroimaging studies and neuroanatomical analysis at both the screening/induction and chronic stages; (c) performance of basic neuropsychological studies at the time of screening/induction and at the chronic stage; (b) statistical analysis as needed by different projects; (c) monitoring of all matters pertaining to subject confidentiality, informed consent procedures, data quality and research progress. These operations, which are essential for the execution of all studies in our Program involving humans, are carried on continuously. They have been carried out smoothly, in all aspects, for the duration of the Program, and remain unchanged for the forthcoming period. The investigators in the Program have also continued to develop new techniques required to improve the quality of neuroanatomical and neuropsychological data gathering and analysis. As a result, new products are now available, to this research group and to others, for cognitive neuroscience research (e.g., single-channel tissue segmentation, 3- dimensional lesion analysis in a standard anatomical space (the MAP-3 technique)).

核心项目是该计划的核心资源。它由五个核心单位组成，这些单位开展下列业务：(A)病人登记处，负责确定、筛选和将受试者纳入登记处，以及神经解剖学和神经心理学数据的中央数据库和数据管理；(B)在筛查/入职阶段和慢性阶段进行神经成像研究和神经解剖学分析；(C)在筛查/入职阶段和慢性阶段进行基础神经心理学研究；(B)根据不同项目的需要进行统计分析；(C)监测与受试者保密、知情同意程序、数据质量和研究进展有关的所有事项。这些操作对于我们计划中所有涉及人类的研究的执行是必不可少的，这些操作将持续进行。在本计划期间，它们在所有方面都得到了顺利执行，并在即将到来的时期保持不变。该计划的研究人员还继续开发提高神经解剖学和神经心理学数据收集和分析质量所需的新技术。因此，现在可以为这个研究小组和其他研究小组提供用于认知神经科学研究的新产品(例如，单通道组织分割、标准解剖空间中的三维病变分析(MAP-3技术))。