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New Scanning Methods for 3-D Breast Ultrasound

3D 乳腺超声新扫描方法

基本信息

批准号：
7057312
负责人：
JESSE T-P YEN
金额：
$ 17.1万
依托单位：
UNIVERSITY OF SOUTHERN CALIFORNIA
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
起止时间：
2005-05-01 至 2009-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7057312
关键词：
bioimaging /biomedical imaging breast neoplasms image enhancement image guided surgery /therapy image processing technology /technique development three dimensional imaging /topography

项目摘要

DESCRIPTION (provided by applicant): The objective of this proposal is to develop a novel 3-D ultrasound system for in vivo imaging of targets near the skin surface such as lesions in the breast. Typical ultrasound systems use a one-dimensional linear array operating in the 7-13 MHz range to produce two-dimensional tomographic scans of the breast. The results of such a scan can depend heavily on skill of the user since he/she must mentally integrate several images to gain an understanding of the three-dimensional anatomy. In addition, the success of ultrasound-guided biopsies can largely depend on the skill of the operator since the needle must be perfectly aligned within a single scan plane. However, a system capable of in vivo imaging of the breast in three dimensions could help alleviate some of these problems and therefore show improved clinical value over today's commercial systems. Using an innovative combination of synthetic aperture methods and a novel interconnect scheme, a 256 x 256 10 MHz 2-D array will be designed, prototyped and fabricated. This new system will allow for the synthesis of a fully sampled 2-D array capable of dynamic focusing in azimuth and elevation. To demonstrate proof of concept, a prototype transducer will be integrated with a 64 channel ultrasound research platform used to gather the necessary echo information needed to produce rectilinear 3-D volumes. A series of water tank and tissue phantom experiments will be performed to evaluate imaging performance in terms of resolution, contrast, and signal-to-noise ratio.

描述（由申请人提供）：该提案的目的是开发一种新型 3D 超声系统，用于对皮肤表面附近的目标（例如乳房病变）进行体内成像。典型的超声系统使用工作频率为 7-13 MHz 的一维线性阵列来生成乳房的二维断层扫描。这种扫描的结果在很大程度上取决于用户的技能，因为他/她必须在心里整合多个图像以获得对三维解剖结构的理解。此外，超声引导活检的成功很大程度上取决于操作员的技能，因为针必须在单个扫描平面内完美对齐。然而，能够对乳房进行三维体内成像的系统可以帮助缓解其中一些问题，因此比当今的商业系统显示出更高的临床价值。使用合成孔径方法和新颖的互连方案的创新组合，将设计、原型化和制造256 x 256 10 MHz 2-D阵列。这个新系统将允许合成一个完全采样的二维阵列，能够在方位角和仰角上进行动态聚焦。为了演示概念验证，原型换能器将与 64 通道超声研究平台集成，用于收集产生直线 3D 体积所需的必要回波信息。将进行一系列水箱和组织体模实验，以评估分辨率、对比度和信噪比方面的成像性能。