Physician Scientist Research Training in Pathogenesis of Viral Diseases

病毒性疾病发病机制的医师科学家研究培训

• 批准号: 7122740
• 负责人: Mary E. Klotman
• 金额: $ 12.86万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-08-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7122740
• 关键词: Physician; Scientist; Research; Training; Pathogenesis

DESCRIPTION (provided by applicant): Viral diseases continue to be a major threat to both the pediatric as well as the adult patient population. In recent years, the rapid emergence and spread of relatively new human pathogens such as HIV and SARS, the increasing morbidity and mortality associated with persistent and prolonged infection with agents such as Hepatitis C as well as the episodic and often unexplained reemergence of pathogens underscores the necessity of having well trained investigators that can respond rapidly to these public health demands. The goal of this research training grant is to prepare physicians (MD and MD/PhDs) to pursue careers as independent investigators specifically in the area of viral pathogenesis with a primary focus on virus/host interactions. Each of the twelve faculty members representing the key training personnel for this program has a strong track record in the area of viral pathogenesis as reflected in both publications as well as funding and a commitment to training physician-scientists. Each plays a major role in the graduate school as well as their respective departments and has developed extensive collaborative interactions which will provide the trainee a critical and accessible network of expertise. The institutional commitment in this area is reflected by the recent creation of the Emerging Infections Center that will allow continued recruitment of outstanding faculty to reflect Mt. Sinai and will provide an additional framework for trainees to benefit from the interdisciplinary nature of research in this arena. The training program is designed to extend the training period of physicians following completion of their clinical fellowships, particularly in Adult and Pediatric Infectious Diseases. The candidates will enter into their research training track in their second year of fellowship and will be candidates for funding through the training grant for two subsequent years. The major activity (representing 90% of their time) during these two years will be mentored laboratory investigation on an individual project. This experience will be complemented by participation in a weekly journal club, weekly laboratory data sessions as well as divisional, departmental, and institutional research conferences. The goal of this program is to provide the candidate with the necessary skills and training to effectively compete for mentored scientist awards as the next step in their transition to independent careers as physician scientists.

描述（由申请方提供）：病毒性疾病仍然是儿科和成人患者人群的主要威胁。近年来，相对较新的人类病原体（如HIV和SARS）的迅速出现和传播，与丙型肝炎等病原体的持续和长期感染相关的发病率和死亡率的增加，以及病原体的偶发性和经常无法解释的重新出现，都强调了拥有训练有素的调查人员的必要性，这些调查人员可以迅速应对这些公共卫生需求。这项研究培训补助金的目标是准备医生（MD和MD/PhD）追求职业生涯作为独立的调查人员，特别是在病毒发病机制领域，主要侧重于病毒/宿主相互作用。每一个代表该计划的关键培训人员的12名教师都在病毒发病机制领域有着良好的记录，这反映在两个出版物以及资金和培训医生科学家的承诺。每个人都在研究生院及其各自的部门中发挥着重要作用，并开发了广泛的协作互动，这将为受训者提供关键和可访问的专业知识网络。在这一领域的机构承诺反映了新兴感染中心，将允许继续招聘优秀的教师，以反映山最近创建。西奈和将提供一个额外的框架，学员受益于跨学科性质的研究在这个竞技场。该培训计划旨在延长医生完成临床研究金后的培训时间，特别是在成人和儿童传染病方面。候选人将在获得研究金的第二年进入研究培训轨道，并将成为随后两年通过培训补助金供资的候选人。这两年的主要活动（占他们90%的时间）将是指导单个项目的实验室研究。这种经验将通过参加每周的期刊俱乐部，每周的实验室数据会议以及部门，部门和机构的研究会议来补充。该计划的目标是为候选人提供必要的技能和培训，以有效地竞争指导科学家奖，作为他们过渡到独立职业的下一步医生科学家。