Targeted Research and Academic Training of Nurses in Genomics

基因组学护士的针对性研究和学术培训

• 批准号: 7066201
• 负责人: JANICE S DORMAN
• 金额: $ 8.93万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7066201
• 关键词: Targeted; Research; Academic; Training; Nurses

DESCRIPTION (provided by applicant): With the completion of the Human Genome Project, genetic testing for disease susceptibility, diagnosis, treatment, and prognosis has the potential to become part of mainstream medical care and, consequently, impact patient outcomes of interest to nursing. These advancements were made, and continue to be made, because of innovations in genomics research. However, the translation of findings from the laboratory to the community has lagged far behind the generation of new scientific knowledge. As a result, there has been an increasing emphasis on interdisciplinary research initiatives, such as those the initiatives that comprise the NIH Roadmap. Nurses are uniquely positioned to bridge the gap between genomics research and clinical practice. Nurses are the largest and most trusted group of professional health care providers. They interact with patients at all stages of life, and in all clinical arenas. Their work is interdisciplinary by nature. More nurses are now received training in genomics because of its recent introduction in nursing curricula. In addition, the 2003 Institute of Medicine's report "New Horizons in Health" emphasized research priorities, one of which was genomics, that will be required to achieve major improvements in health. The importance of genomics in nursing has been echoed at the National Institute of Nursing Research. Nevertheless, there continue to be few opportunities for long-term laboratory-based training in the conduct of cutting-edge genomics research. Such training opportunities are essential, and must become available because nearly every condition studied by nursing scientists, including those on the faculty of the University of Pittsburgh, School of Nursing, has a genetic component. These represent acute (e.g., infectious disease), as well as chronic disorders, such as obesity, diabetes, cardiovascular disease, osteoporosis, and mental illness to name a few. Our objective is to train talented nursing scientists, at the beginning stages of their careers, to develop research trajectories related to the application and evaluation of genomics in improving patient outcomes. The goal of the proposed training program is to prepare pre- and postdoctoral nursing scientists to incorporate genomics into their research trajectories using didactic courses, clinical rotations, journal clubs, seminars, individualized practice and laboratory experiences, and presentations at scientific meetings. Specific aims focus on training in: 1) the integration of genomics into theoretical / conceptual frameworks, 2) genomics research methodology (e.g., family studies, genome-wide association studies), 3) genomics laboratory techniques, and 4) clinical application of genomics. Reasons why the School of Nursing at the University of Pittsburgh is an ideal environment for the development of such a training program are elaborated in the application.

描述（由申请人提供）：随着人类基因组计划的完成，用于疾病易感性、诊断、治疗和预后的基因检测有可能成为主流医疗护理的一部分，从而影响护理人员感兴趣的患者结局。这些进步是由于基因组学研究的创新而取得的，并将继续取得。然而，从实验室到社区的成果转化远远落后于新科学知识的产生。因此，人们越来越重视跨学科研究计划，例如构成NIH路线图的计划。护士在弥合基因组学研究和临床实践之间的差距方面具有独特的地位。护士是最大和最值得信赖的专业医疗保健提供者群体。他们在生命的各个阶段和所有临床领域与患者互动。他们的工作本质上是跨学科的。由于最近在护理课程中引入了基因组学，现在有更多的护士接受了基因组学方面的培训。此外，2003年医学研究所的报告“健康的新视野”强调了研究的优先事项，其中之一是基因组学，这是实现健康的重大改善所必需的。基因组学在护理中的重要性得到了国家护理研究所的回应。然而，在进行尖端基因组学研究方面，长期在实验室接受培训的机会仍然很少。这样的培训机会是必不可少的，必须成为可用的，因为几乎每一个条件研究的护理科学家，包括那些在匹兹堡大学护理学院的教师，有一个遗传成分。这些代表急性（例如，感染性疾病），以及慢性疾病，例如肥胖症、糖尿病、心血管疾病、骨质疏松症和精神疾病，仅举几例。我们的目标是培养有才华的护理科学家，在他们的职业生涯的开始阶段，开发相关的应用和评估基因组学在改善患者的结果研究轨迹。拟议的培训计划的目标是准备前和博士后护理科学家将基因组学纳入他们的研究轨迹使用教学课程，临床轮换，期刊俱乐部，研讨会，个性化的实践和实验室经验，并在科学会议上演示。具体目标侧重于以下方面的培训：1）将基因组学纳入理论/概念框架，2）基因组学研究方法（例如，家族研究、全基因组关联研究），3）基因组学实验室技术，以及4）基因组学的临床应用。为什么在匹兹堡大学护理学院是一个理想的环境，这样的培训计划的发展的原因进行了详细的说明。