Biomechanically Based Shoulder Rehabilitation Strategies

基于生物力学的肩部康复策略

• 批准号: 7060841
• 负责人: PAULA Marie LUDEWIG
• 金额: $ 11.27万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-06-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7060841
• 关键词: adult human (21+); biomechanics; body movement; clinical research; computed axial tomography; computer program /software; computer simulation; disease /disorder; electromagnetic radiation; human subject; human tissue; image processing; joint disorder; muscle function; musculoskeletal system; pathology; patient oriented research; postdoctoral investigator; postmortem; rehabilitation; shoulder

DESCRIPTION (provided by applicant): The candidate's long-term career objective is to investigate biomechanical factors contributing to musculoskeletal dysfunction, in order to refine current clinical treatment approaches and develop novel scientifically founded rehabilitation interventions. A five-year research and training plan developed with the primary mentor and a team of experienced scientists will expand the candidate's scientific background in biomechanics and musculoskeletal modeling, enrich her direct research skills and experience in the scientific process, promote integration of research findings to clinical practice, and advance skills necessary for becoming an independent investigator. The long-term objective of the research plan is to develop and test the effectiveness of biomechanically based rehabilitation strategies for improving upper extremity function and reducing pain and disability in persons with shoulder pathologies related to abnormal shoulder movement patterns. In-vivo 3-D full shoulder complex kinematics (thorax, clavicle, scapula, and humerus) during arm elevation will be collected from healthy and symptomatic subjects and integrated with a state of the art shoulder model to describe the 3-D muscle function of selected shoulder muscles, allowing comparisons among muscles for their relative biomechanical ability to reduce shoulder kinematic deviations, or contribute to deviations if producing excess or inadequate force (Aim 1). Computerized Tomography scans of the shoulder complex structures will be taken and imaging data combined with the kinematic data, allowing determination of the effects of abnormal kinematics on the available volume of the subacromial space, providing insight into how specific kinematic deviations create impingement of soft tissue structures (Aim 2). Determining and demonstrating muscle activations that can improve scapular kinematics and reduce subacromial impingement can provide a template for scientifically based intervention approaches that can be further tested through clinical trials.

描述（由申请人提供）：候选人的长期职业目标是研究导致肌肉骨骼功能障碍的生物力学因素，以完善当前的临床治疗方法，并开发新的科学康复干预措施。与主要导师和经验丰富的科学家团队一起开发的五年研究和培训计划将扩大候选人在生物力学和肌肉骨骼建模方面的科学背景，丰富她在科学过程中的直接研究技能和经验，促进研究成果与临床实践的整合，并提高成为独立研究者所需的技能。该研究计划的长期目标是开发和测试基于生物力学的康复策略的有效性，以改善上肢功能，减少与异常肩部运动模式相关的肩部病变患者的疼痛和残疾。体内三维全肩关节复杂运动学将从健康和有症状的受试者中收集手臂抬高期间的肩关节（胸部、锁骨、肩胛骨和肱骨），并与最先进的肩关节模型相结合，以描述所选肩关节肌肉的3-D肌肉功能，允许比较肌肉之间减少肩关节运动学偏差的相对生物力学能力，或在产生过大或不足的力时导致偏差（目标1）。 将对肩关节复杂结构进行计算机断层扫描，并将成像数据与运动学数据相结合，以确定异常运动学对肩峰下空间可用体积的影响，从而深入了解特定运动学偏差如何造成软组织结构撞击（目标2）。确定和证明可以改善肩胛骨运动学并减少肩峰下撞击的肌肉激活可以为基于科学的干预方法提供模板，这些方法可以通过临床试验进一步测试。