Prospective Study of UEMSD and Physical Job Stressors

产品说明：四肢肌肉骨骼疾病（UEMSD）影响手、臂、肩和颈的肌腱、腱鞘、肌肉、神经、囊和血管。 2000年，与反复创伤有关的疾病“占美国所有与工作有关的疾病的67%。 身体工作压力源和UEMSDs之间的不一致的关联通常被报道。 这些不一致与暴露测量不精确、混杂控制不完全、 健康结果，几乎完全依赖于横断面设计的研究。 为了更好地评估工作对肌肉骨骼健康的影响， 制造业工人提出。 将在1.5年内入组约600例研究受试者，并随访长达3年。 入组时，将记录肌肉骨骼症状，并收集人口统计学、个人健康、工作史和职业心理社会压力信息。 有关暴露于物理工作压力源的信息将从两个来源的组合中获得。 首先，对于每名研究参与者，将通过观察和直接方法量化与其工作中执行的所有任务相关的用力、上肢重复和上肢姿势。 其次，要求所有研究参与者每天在任务日志中记录他/她执行其工作所需的每项特定任务所花费的小时数。 每项任务的体力工作压力源将与每个参与者随时间执行的特定任务日志中的信息相结合，以创建一个独特的暴露信息时间序列。 对员工任务的任何更改都将记录在任务日志中，并将触发风险重新评估。 研究参与者还将记录上肢症状的发生率和严重程度。 符合先验标准的新发症状的受试者将接受标准临床检查。 将解决两个主要目标：1）将在制造工人中估计特定UEMSD的发生率，2）将进行包含时变自变量的多变量分析，以检验UEMSD事件与物理工作压力源相关的假设（在控制潜在混杂变量后）。

DESCRIPTION: Musculoskeletal disorders of the extremities (UEMSDs) affect tendons, tendons sheaths, muscles, nerves, bursae, and blood vessels of the hands arms, shoulders, and neck. In 2000, disorders associated with repeated trauma "accounted for 67% of all work-related illness in the United States. Inconsistent associations between physical job stressors and UEMSDs are commonly reported. These inconsistencies are related to imprecise measures of exposure, incomplete control of confounding, poor ascertainment of health outcome, and near exclusive reliance on studies of cross-sectional design. To better estimate effects of work on musculoskeletal health, a prospective epidemiologic study of manufacturing workers is proposed. Approximately 600 study participants will be enrolled over 1.5 years and followed for up to 3 years. At the time of enrolment, musculoskeletal symptoms will be documented and demographic, personal health, work history, and occupational psychosocial stress information will be collected. Information about exposure to physical job stressors will be obtained from a combination of two sources. First, for each study participant, forceful exertions, upper extremity repetition, and upper extremity postures associated with all tasks performed at his/her job will be quantified by observations and direct methods. Second, all study participants will be asked to record in a task log, on a daily basis, the number of hours he/she spent performing each of the specific tasks that are required by his/her job. The physical job stressors for each task will be combined with information from each participant's log of specific tasks performed over time to create a unique time series of exposure information. Any changes to the employee's tasks will be recorded in the task log and will trigger and exposure reassessment. Study participants will also record occurrences and severity of upper extremity symptoms. Those participants with new onset of symptoms that meet a priori criteria will undergo standard clinical examination. Two primary aims will be addressed: 1) the incidence of specific UEMSDs will be estimated among manufacturing workers and 2) multivariate analyses that incorporate time-varying independent variables will be performed to test the hypothesis that incident UEMSDs are associated with physical job stressors after controlling for potential confounding variables.