Egypt Smoking Prevention Research Initiative

埃及预防吸烟研究计划

• 批准号: 7098053
• 负责人: Christopher A Loffredo
• 金额: $ 49.51万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-07-01 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7098053
• 关键词: Egypt; clinical research; cooperative study; disease /disorder proneness /risk; epidemiology; gene environment interaction; genetic susceptibility; health education; health science research; human genetic material tag; human subject; nicotine; passive smoking; physicians; questionnaires; smoking; tobacco abuse; tobacco abuse prevention; training; workshop; young adult human (21-34)

DESCRIPTION (provided by applicant): Egypt is the most populous country in the Middle East. It serves as a bridge between the West and the Arab countries. Cigarette and water pipe smoking and medical complications of tobacco use are increasing at an alarming rate. Half of male Egyptian physicians are smokers. The overall goal of this initiative is to establish research and capacity building projects to reduce tobacco use in Egypt. We propose to carry out observational, interventional and policy research in Egypt and build capacity for smoking prevention. Specific Aims are: 1) create the Egyptian Smoking Prevention Research Institute (ESPRI) to perform smoking prevention research within the Ministry of Health and Population (MOHP) and to become a World Health Organization Collaborating Center; 2) implement epidemiological surveillance and research on tobacco use, tobacco harm and risk factors for tobacco use including studies of special relevance to Egypt, e.g. smoking water pipes and monitoring the high smoking rate among physicians; 3) conduct molecular epidemiology research to identify genetic and environmental risk factors associated with addiction and tobacco harm; 4) conduct intervention research to reduce community second-hand tobacco smoke in villages and reduce cigarette and water pipe smoking in physicians and young adults; 5) carry out policy research to study implementation, enforcement, and enactment of laws and regulations to protect the public from tobacco harm; 6) build capacity and strengthen infrastructure by long- and short-term training of health care providers, health educators, government workers, laboratory personnel and non-governmental organizations. Lasting partnerships will be established between U.S. and Egyptian investigators. Research associates will be trained on tobacco-related issues through their work on these projects. Training workshops will be conducted for MOHP staff and media groups. In addition, the formation of a tobacco control coalition will strengthen the role of non-governmental organizations as partners in tobacco control. The proposed studies will add significantly to the current knowledge base in tobacco control efforts specific to Egypt. The establishment of the ESPRI and the professional development of Egyptian investigators and Research Associates will accelerate Egypt's efforts to become tobacco free.

描述（由申请人提供）： 埃及是中东人口最多的国家。它是西方和阿拉伯国家之间的桥梁。吸烟和水管吸烟以及烟草使用的医疗并发症正在以惊人的速度增加。一半的男性埃及医生是吸烟者。该计划的总体目标是建立研究和能力建设项目，以减少埃及的烟草使用。我们建议在埃及进行观察，介入和政策研究，并增强预防吸烟能力。具体目的是：1）创建埃及吸烟预防研究所（ESPRI），以在卫生与人口部（MOHP）（MOHP）进行预防吸烟研究，并成为世界卫生组织的合作中心； 2）实施有关烟草使用，烟草危害和烟草使用风险因素的流行病学监测和研究，包括与埃及的特殊相关性研究，例如吸烟管道并监测医生的高吸烟率； 3）进行分子流行病学研究，以确定与成瘾和烟草危害相关的遗传和环境风险因素； 4）进行干预研究，以减少村庄中的二手烟草烟雾，并减少医生和年轻人的香烟和水管吸烟； 5）进行政策研究，以研究法律和法规的实施，执行和制定，以保护公众免受烟草伤害； 6）通过对医疗保健提供者，健康教育者，政府工作人员，实验室人员和非政府组织的长期和短期培训来建立能力并加强基础设施。美国和埃及调查人员之间将建立持久的伙伴关系。研究助理将通过在这些项目上的工作进行与烟草有关的问题进行培训。将为MOHP员工和媒体团体举办培训讲习班。此外，烟草控制联盟的形成将加强非政府组织作为烟草控制中的合作伙伴的作用。拟议的研究将大大增加特定于埃及的烟草控制工作的当前知识基础。 ESPRI的建立以及埃及调查人员和研究伙伴的专业发展将加速埃及自由烟草的努力。

项目成果

Evaluation of Papanicolaou stain for studying micronuclei in buccal cells under field conditions.

评估巴氏染色在现场条件下研究口腔细胞微核的效果。

• DOI: 10.1159/000325980
• 发表时间: 2006
• 期刊: Acta cytologica
• 影响因子: 1.8
• 作者: Ayyad,SohairBA;Israel,Ebenezer;El-Setouhy,Maged;Nasr,GhadaRadwan;Mohamed,MostafaK;Loffredo,ChristopherA
• 通讯作者: Loffredo,ChristopherA

Assessment of tobacco dependence in waterpipe smokers in Egypt.

• DOI: 10.5588/ijtld.11.0457
• 发表时间: 2012-01
• 期刊: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
• 作者: Auf RA;Radwan GN;Loffredo CA;El Setouhy M;Israel E;Mohamed MK
• 通讯作者: Mohamed MK

Waterpipe Smoking And The DRD2/ANKK1 Genotype.

水烟吸烟和 DRD2/ANKK1 基因型。

• 发表时间: 2010
• 期刊: The Journal of the Egyptian Public Health Association
• 作者: Radwan,GhadaN;Loffredo,ChristopherA;ElSetouhy,MagedA;AbdelHamid,Mohamed;Israel,EbenezerJ;Mohamed,MostafaK
• 通讯作者: Mohamed,MostafaK