Boston University Aphasia Research Core Center

波士顿大学失语症研究核心中心

• 批准号: 6941761
• 负责人: MARTIN L ALBERT
• 金额: $ 57.5万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-26 至 2007-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6941761
• 关键词: aphasia; biomedical facility

DESCRIPTION (provided by applicant): The principal objectives of the Aphasia Research Core Center are to recruit research participants and to provide clinical assessment and data management and analysis services for research projects that advance the theoretical understanding, clinical evaluation, and treatment of language disorders produced by injury or dysfunction of the brain in adults. The Aphasia Research Core Center consists of two cores: a Clinical Assessment Core and a Data Management and Analysis (DAMA) Core, together with administrative support for these cores. The Clinical Assessment Core recruits research participants, provides comprehensive assessments of aphasic, right brain damaged, and healthy elderly subjects, and coordinates their participation in all research projects associated with the Core Center. Assessment Core examinations include four major components: a medical/neurological evaluation by a behavioral neurologist, a language evaluation, a neuropsychological evaluation, and a neuroimaging evaluation. The Data Management and Analysis Core provides a comprehensive database of all assessment and research data for each research participant. The primary objectives of this core are to manage the data obtained by members of the Clinical Assessment Core and all research projects, to make the data accessible to all ARC researchers, and to provide research design and statistical support for on-going analysis of data and development of new research protocols. The DAMA core has three major service areas: data management, research design and statistical analysis, and education of research investigators. To achieve the overall goals of the Core Center, we intend to support research on language and aphasia within different, but interrelated, disciplines simultaneously. The unifying agenda of the Core Center will be to integrate these various approaches to arrive at a coherent picture of how language is represented in the brain.

描述（由申请人提供）：失语症的主要目标 研究核心中心负责招募研究参与者并提供 研究的临床评估以及数据管理和分析服务 促进理论理解、临床评估和 治疗由大脑损伤或功能障碍引起的语言障碍 在成人中。失语症研究核心中心由两个核心组成：临床 评估核心和数据管理和分析 (DAMA) 核心，以及 对这些核心的行政支持。 临床评估核心招募研究参与者，提供 对失语症、右脑受损和健康老年人的综合评估 主题，并协调他们对所有研究项目的参与 与核心中心相关。评估核心考试包括四项主要内容 组成部分：由行为神经学家进行的医学/神经学评估， 语言评估、神经心理学评估和神经影像学评估 评估。 数据管理和分析核心提供了所有信息的综合数据库 每个研究参与者的评估和研究数据。初级 该核心的目标是管理成员获得的数据 临床评估核心和所有研究项目，使数据易于访问 向所有 ARC 研究人员提供研究设计和统计支持 用于持续分析数据和开发新的研究方案。这 DAMA核心有三大服务领域：数据管理、研究设计和 统计分析和研究人员的教育。 为了实现核心中心的总体目标，我们打算支持研究 关于不同但相互关联的学科中的语言和失语症 同时地。核心中心的统一议程将是整合 这些不同的方法可以对语言的运作方式有一个连贯的认识 代表在大脑中。