Clinical Core

临床核心

• 批准号: 7668480
• 负责人: MARTIN L ALBERT
• 金额: $ 25.71万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7668480
• 关键词: Aphasia; Area; Behavioral; Boston; Brain; Brain Injuries; Clinic; Clinical; Clinical Treatment; Clinical Trials; Clinical assessments; Cognitive; Communication impairment; Development; Disease; Evaluation; Grant; Hospitals; Impaired cognition; Incubators; Individual; Language; Left; Linguistics; Medical; Nervous System Physiology; Neurologic; Neurologist; Participant; Pathologist; Pattern; Radiology Specialty; Recruitment Activity; Research; Research Personnel; Research Project Grants; Services; Specialist; Speech; Staging; Techniques; Testing; Time; Translational Research; United States National Institutes of Health; bench to bedside; cost; neurobehavioral; neuroimaging; neuropsychological; programs; research study; response

Core A. Clinical Assessment Core The Clinical Assessment Core recruits and provides comprehensive assessments of research participants, and coordinates their participation in affiliated research projects. Brain-damaged individuals may be quite dissimilar in their patterns of cognitive dysfunction. Thus research projects affiliated with the HGARC are dependent oh a comprehensive understanding of each participant's neurological, neuroimaging, neurobehavioral, neuropsychological, and language status. The Clinical Assessment Core examination consists of four major components: (1) a medical/neurological evaluation conducted by a behavioral neurologist, (2) a speech/language evaluation conducted by a speech-language pathologist, (3) a neuropsychological evaluation conducted by a neuropsychologist, and (4) neuroimaging performed by the radiology service of affiliated hospitals and interpreted by the Assesement Gore neuroimaging specialists. In addition to recruitment and testing of participants with left- or right-hemispheric brain damgage, the Clinical Assessment Core also recruits and screens matched control subjects. Newly added to our Clinical Assessment Core during the current grant cycle is the Extended Assessment Clinic, used to assess over . time a subject's response to cognitive-linguistic treatment techniques in an early, developmental stage. This new program responds directly to NIH initiatives for translational research, and, as documented in this proposal, has already succeeded in serving as an incubator for new bench-to-bedside research. The Harold Goodglass Aphasia Research Center has been providing recruitment and clinical assessment services to Boston-area researchers since its founding in the 1960s and is internationally recognized for its expertise in the assessment and treatment of people with communication impairments. Recruiting research participants for aphasia and aphasia related research is costly and labor-intensive. Researchers have come to rely on the HGARC for its comprehensive, efficient, and cost-effective support.

核心A.临床评估核心 临床评估核心招募并提供对研究参与者的全面评估， 并协调他们参与附属研究项目。大脑受损的人可能会相当 他们的认知功能障碍模式不同。因此，隶属于HGARC的研究项目是 依赖于对每个参与者的神经学、神经成像、 神经行为、神经心理和语言状态。临床评估核心考试 由四个主要部分组成：(1)由行为人进行的医学/神经学评估 神经科医生，(2)由言语语言病理学家进行的言语/语言评估，(3)a 由神经心理学家进行的神经心理评估，以及(4)由 附属医院的放射科服务，并由戈尔神经影像专家评估解释。在……里面 除了招募和测试患有左半球或右半球脑损伤的参与者外，临床 评估核心还招募和筛选匹配的对照受试者。新加入我们的临床 在当前赠款周期中，评估的核心是扩展评估诊所，用于评估Over。 在早期发展阶段，对受试者对认知语言治疗技术的反应进行计时。这 新的计划直接响应了NIH的翻译研究倡议，如本文件中所述 这一提议已经成功地成为新的床到床研究的孵化器。哈罗德家族 古德格拉斯失语症研究中心一直为以下人员提供招聘和临床评估服务 自20世纪60年代成立以来，波士顿地区的研究人员一直以其在以下方面的专业知识而闻名国际 对有沟通障碍的人的评估和治疗。招募研究参与者 对于失语症和失语症，相关研究是昂贵和劳动密集型的。研究人员已经开始依赖于 HGARC对其全面、高效和具有成本效益的支持表示赞赏。