Boston University Aphasia Research Core Center

描述（由申请人提供）：失语症的主要目的 研究核心中心招募研究参与者，并提供 临床评估、数据管理和分析服务 推进理论理解、临床评价和 治疗由脑损伤或功能障碍引起的语言障碍 在成年人中。失语症研究核心中心由两个核心组成：临床 评估核心和数据管理与分析（DAMA）核心，以及 为这些核心提供行政支持。 临床评估核心招募研究参与者，提供 失语症、右脑损伤和健康老年人的综合评估 学科，并协调他们参与所有研究项目 与核心中心有关。核心考试包括四个主要部分 组成部分：行为神经学家的医学/神经学评估， 语言评估，神经心理评估和神经成像 评价 数据管理和分析核心提供了一个全面的数据库， 每个研究参与者的评估和研究数据。主 该核心的目标是管理成员获得的数据， 临床评估核心和所有研究项目，使数据可访问 所有ARC研究人员，并提供研究设计和统计支持 用于持续的数据分析和新研究方案的开发。的 DAMA核心有三大服务领域：数据管理、研究设计和 统计分析和研究人员的教育。 为了实现核心中心的总体目标，我们打算支持研究 在不同但相互关联的学科中研究语言和失语症 同步核心中心的统一议程将是整合 这些不同的方法，以达到一个连贯的图片，语言是如何 在大脑中表现出来。

DESCRIPTION (provided by applicant): The principal objectives of the Aphasia Research Core Center are to recruit research participants and to provide clinical assessment and data management and analysis services for research projects that advance the theoretical understanding, clinical evaluation, and treatment of language disorders produced by injury or dysfunction of the brain in adults. The Aphasia Research Core Center consists of two cores: a Clinical Assessment Core and a Data Management and Analysis (DAMA) Core, together with administrative support for these cores. The Clinical Assessment Core recruits research participants, provides comprehensive assessments of aphasic, right brain damaged, and healthy elderly subjects, and coordinates their participation in all research projects associated with the Core Center. Assessment Core examinations include four major components: a medical/neurological evaluation by a behavioral neurologist, a language evaluation, a neuropsychological evaluation, and a neuroimaging evaluation. The Data Management and Analysis Core provides a comprehensive database of all assessment and research data for each research participant. The primary objectives of this core are to manage the data obtained by members of the Clinical Assessment Core and all research projects, to make the data accessible to all ARC researchers, and to provide research design and statistical support for on-going analysis of data and development of new research protocols. The DAMA core has three major service areas: data management, research design and statistical analysis, and education of research investigators. To achieve the overall goals of the Core Center, we intend to support research on language and aphasia within different, but interrelated, disciplines simultaneously. The unifying agenda of the Core Center will be to integrate these various approaches to arrive at a coherent picture of how language is represented in the brain.