The ALS Locked-in Communicator

ALS 锁定通讯器

• 批准号: 7109730
• 负责人: Robert N Schmidt
• 金额: $ 19.39万
• 依托单位: CLEVELAND MEDICAL DEVICES, INC.
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2010-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7109730
• 关键词: clinical research; communication; emotions; muscle; syndrome

DESCRIPTION (provided by applicant): Standard Assistive Technology (AT) solutions do not help people with locked-in syndrome because most AT input devices depend on some form of small but reliable muscle movement, such as pressing a button, eye movements, or blinking. This program will provide a simple device to take standard AT technology to the next level with Biometric Interfaces. This program will develop a four-mode communication aid for disabled individuals. Since a large share of its market will be advanced stage Amyotrophic Lateral Sclerosis (Lou Gehrigs Disease, or ALS) patients and other locked-in patients, it will be referred to "The ALS Locked-ln COmmunicatoR, or TALCOR (pronounced "TALKER"). The goal of this program is to develop and validate a new device that allows severely disable individuals who cannot communicate to do so. TALCOR will provide four different methods of non-traditional communications: 1. Brain Computer Interface (BCI) using EEG; 2. Galvanic Skin Response (GSR). 3. pH changes in the mouth; and 4. Amplified and filtered muscle movement, EMG: In Phase I, we will build a prototype TALCOR that will demonstrate all four modes on the lab bench and with healthy volunteers, and at least one of these methods (or modes) of communication with a patient that currently does not have the ability to communicate. In Phase II, we will upgrade the selected communication modes, harden the device, improve the software, enhance the design toward manufacturing and commercialization, and test the device on patients in the modes selected in Phase I to show its utility.

描述(申请人提供)：标准辅助技术(AT)解决方案不能帮助患有闭锁综合症的人，因为大多数AT输入设备依赖于某种形式的微小但可靠的肌肉运动，如按下按钮、眼睛运动或眨眼。该计划将提供一个简单的设备，通过生物识别接口将标准AT技术提升到一个新的水平。该项目将为残疾人开发四种模式的交流辅助工具。由于其市场的很大份额将是晚期肌萎缩侧索硬化症(Lou Gehrigs病，或ALS)患者和其他闭锁患者，它将被称为“ALS闭锁通信器，或TALCOR(发音为”Talker“)。这个项目的目标是开发和验证一种新的设备，允许严重残疾的无法交流的人这样做。TALCOR将提供四种不同的非传统通信方法：1.使用脑电的脑机接口(BCI)；2.皮肤电反应(GSR)。3.口腔内PH值的变化；4.放大和过滤的肌肉运动，肌电：在第一阶段，我们将建立一个原型TALCOR，它将在实验室工作台上和健康志愿者身上演示所有四种模式，以及这些方法中的至少一种(或几种模式)与目前没有沟通能力的患者交流。在第二阶段，我们将升级选定的通信模式，硬化设备，改进软件，向制造和商业化方向加强设计，并在第一阶段选择的模式下在患者身上测试设备，以展示其实用性。