Optimizing a Social Connectedness Intervention for Young Adults with Cancer

优化年轻癌症患者的社会联系干预

• 批准号: 10734095
• 负责人: BARBARA LEE FREDRICKSON
• 金额: $ 68.05万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-01 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10734095
• 关键词: Address; Age; Basic Science; Behavior Therapy; Behavioral; Cellular Phone; Communication; Cues; Data; Data Analyses; Effectiveness of Interventions; Emotional; Emotions; Evidence based intervention; Goals; Health; Heavy Drinking; Human; Image; Imagery; Individual; Intervention; Interview; Knowledge; Life; Malignant Neoplasms; Measures; Mediator; Mental Health; Meta-Analysis; Motivation; Obesity; Oncology; Outcome; Participant; Personal Satisfaction; Persons; Placebo Control; Population; Protocols documentation; Psychology; Quality of life; Randomized; Randomized, Controlled Trials; Reporting; Reproducibility; Research; Risk Factors; Sampling; Science; Social Environment; Social Psychology; Social isolation; Statistical Models; Symptoms; Testing; Text; Tobacco use; Translations; Underserved Population; United States; Visual; Vulnerable Populations; Well in self; Work; behavioral adherence; cancer diagnosis; cost; demographics; design; digital; digital delivery; digital intervention; effective intervention; emerging adult; evidence base; experience; experimental study; health communication; improved; intervention effect; mortality; multidisciplinary; novel; peer; pilot test; positive emotional state; post intervention; primary outcome; programs; promote resilience; psychologic; psychological distress; psychosocial; secondary outcome; sedentary; social; social interventions; social media; theories; therapy design; young adult

PROJECT SUMMARY/ABSTRACT Young adults with cancer need tailored behavioral interventions to improve their psychosocial health. Any cancer diagnosis in early adulthood can create debilitating life disruptions that increase social isolation that in turn can compromise psychosocial health. Social isolation also predicts mortality comparably to other well- established risk factors, including tobacco use, excessive alcohol consumption, obesity, and sedentary status. This conclusion—described as “unequivocal”—was established by a large-scale meta-analysis and now fuels the call for low-cost and scalable behavioral interventions optimized for vulnerable populations to increase social connectedness. The demand for such interventions is especially pressing for young adults with cancer, whose unique needs have long gone unmet. The broad, overarching objective of this work is to optimize an evidence-based social connectedness intervention for young adults with cancer and test whether it improves their psychosocial health. This intervention, delivered digitally and effective among young adults (noncancer samples), prompts individuals to increase the emotional quality of their in-person social encounters. Our multi- disciplinary team will carry out a rigorous, randomized controlled trial—the Keep Social RCT—using our simulated social media platform to deliver intervention messages optimized for young adults with cancer while collecting repeated measures of day-to-day experiences and psychosocial health outcomes. This program of research is designed to meet three specific aims. SPECIFIC AIM 1 is to optimize our social connectedness intervention for young adults with cancer. This aim will be met using a human-centered communication science approach to enhance the positive reception of health messages with social context cues (human imagery, peer stories), and conduct an online experiment with 400 young adults with cancer to identify the most effective intervention messages for use in the Keep Social RCT. SPECIFIC AIM 2 is to pilot, conduct, and analyze the Keep Social RCT to test whether our social connectedness intervention, delivered via social media, improves psychosocial health in young adults with cancer. After thorough pilot testing, this aim will be met by conducting our placebo controlled Keep Social RCT with repeated assessments over six weeks. These data will allow us to test whether our intervention raises social and emotional well-being (primary outcomes) and improves resilience and negative mental health symptoms (secondary outcomes). SPECIFIC AIM 3 is to extend data analyses of the AIM 2 Keep Social RCT to test theory-based mechanisms and explore moderators of intervention effectiveness to pave the way for further optimization. This aim will be met with statistical modeling to identify how and for whom our social connectedness intervention improves psychosocial health among young adults with cancer. Our multi-disciplinary team brings together expertise in social psychology, emotion science, communication science, and oncology to pursue these aims to produce translation-ready pragmatic knowledge to improve the quality of life among young adults with cancer in the United States.

项目摘要/摘要 患有癌症的年轻人需要量身定制的行为干预措施，以改善其社会心理健康。任何 成年初期的癌症诊断会造成使人衰弱的生活中断，从而增加了社会隔离 转弯会损害社会心理健康。社会隔离还可以预测死亡率与其他良好 已建立的危险因素，包括烟草使用，饮酒过量，肥胖和久坐状态。 这个结论（称为“明确”）是由大规模荟萃分析建立的，现在是燃料 呼吁优化弱势群体的低成本和可扩展行为干预措施增加 社会联系。这种干预措施的需求尤其是对癌症的年轻人的迫切需求， 他们的独特需求早已未满足。这项工作的广泛，总体目标是优化 癌症年轻人的循证社会联系干预措施并测试它是否有所改善 他们的社会心理健康。这种干预措施，在年轻人中以数字方式和有效的方式进行（非癌者） 样本），促使个人提高个人社交遭遇的情感质量。我们的多 纪律团队将进行严格的随机对照试验（保持社交RCT） 模拟社交媒体平台，以提供针对癌症的年轻人优化的干预信息，而 收集重复的日常经历和社会心理健康成果的措施。这个程序的 研究旨在满足三个特定目标。特定目标1是优化我们的社会联系 癌症年轻人的干预。将使用以人为本的传播科学实现此目标 通过社会环境提示（人类图像，同伴 故事），并与400名癌症年轻人进行在线实验，以识别最有效的 干预消息用于保留社交RCT。具体目标2是试行，进行和分析 保持社交RCT测试通过社交媒体提供的社交联系干预是否有所改善 癌症年轻人的社会心理健康。经过彻底的试点测试，将通过进行实现 我们的安慰剂控制的人可以在六个星期内重复评估社交RCT。这些数据将使我们 测试我们的干预是否提高社会和情感福祉（主要结果）并改善 韧性和负面心理健康症状（次要结果）。特定目标3是扩展数据 AIM 2的分析保持社会RCT测试基于理论的机制并探索主持人 干预有效性为进一步优化铺平道路。统计建模将实现此目标 确定我们的社会联系干预如何以及为谁改善了谁的心理健康 年轻人患有癌症。我们的多学科团队汇集了社会心理学，情感的专业知识 购买这些目的的科学，传播科学和肿瘤学旨在产生务实的务实 知识以改善美国患有癌症的年轻人的生活质量。