Confocal Microscope

共焦显微镜

• 批准号: 6878277
• 负责人: TADMIRI Rangachar VENKATESH
• 金额: $ 19.97万
• 依托单位: CITY COLLEGE OF NEW YORK
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-04-01 至 2006-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6878277
• 关键词: biomedical equipment purchase; cell biology; confocal scanning microscopy; developmental neurobiology; hematopoiesis; learning; molecular /cellular imaging; neurogenesis

DESCRIPTION (provided by applicant): This proposal requests funds for a confocal microscope to be used as shared imaging instrument by the faculty in the department of biology at the City College of New York. The confocal microscope will facilitate the research activities of eight NIH-funded investigators some of whom already use confocal microscopy in their research, and will enable others to initiate a new dimension to their ongoing research activities. At the present time there is no confocal microscope available in any of the departments of the Division of science at City College. The current users of the confocal microscopy are using for-fee facilities at other research institutions in New York and Boston. A total of nine principal investigators and over 40 research personnel including postdoctoral fellows, graduate students, undergraduates, and research assistants will use the requested microscope on a daily basis. The research projects of the users cover a diverse variety of confocal applications that include: cellular basis of song learning in birds, neurotransmitter function in nematodes, neuronal development in Drosophila and higher vertebrates, studies on Foraminifera, thymic nurse cell function and Drosophila hematopoiesis and immune response. The use of a confocal microscope is critical for these studies. Funds are requested for a Nikon C1 confocal microscope. This microscope has high quality optics, resolution and excellent image quality and is versatile and compatible to most imaging software. In addition, the low cost of the microscope and quality of service as compared to other manufacturers were important points of concern. The confocal microscope is a key essential instrument and relatively standard in most departments. Acquisition of the confocal microscope will greatly enhance the quality and the productivity of the NIH funded investigators at City College.

描述（由申请人提供）：本提案要求为共聚焦显微镜提供资金，该显微镜将被纽约生物系的教师用作共享成像仪器。共聚焦显微镜将促进八个NIH资助的研究人员的研究活动，其中一些人已经在他们的研究中使用共聚焦显微镜，并将使其他人能够启动一个新的层面，他们正在进行的研究活动。目前，城市学院科学系的任何一个系都没有共聚焦显微镜。目前共聚焦显微镜的用户正在使用纽约和波士顿其他研究机构的收费设施。共有9名主要研究人员和40多名研究人员，包括博士后研究员，研究生，本科生和研究助理将每天使用所需的显微镜。用户的研究项目涵盖各种共聚焦应用，包括：鸟类学习歌曲的细胞基础，线虫的神经递质功能，果蝇和高等脊椎动物的神经元发育，有孔虫，胸腺护士细胞功能和果蝇造血和免疫反应的研究。共聚焦显微镜的使用对于这些研究至关重要。请求提供资金购买Nikon C1共焦显微镜。这款显微镜具有高质量的光学器件、分辨率和出色的图像质量，并且功能多样，兼容大多数成像软件。此外，与其他制造商相比，显微镜的低成本和服务质量也是重要的关注点。共焦显微镜是一种关键的必备仪器，在许多部门都是比较标准的。获得共聚焦显微镜将大大提高城市学院NIH资助的研究人员的质量和生产力。