CTN: Harvard University Northern New England Node

描述(由申请人提供)：这是为NIDAC临床试验网络(CTN)建立哈佛大学北部新英格兰(HUNNE)节点的建议。拟议的节点是学术研究人员和新英格兰5个州的临床治疗计划(CTP)之间的合作伙伴关系。其目标是共同努力，在社区项目中设计和实施成瘾治疗研究，使患者充分受益于不断发展的成瘾治疗科学。HUNNE Node在行为、药理学、联合行为/药理学和健康服务成瘾研究领域拥有专业知识。HUNNE Node的研究人员来自哈佛大学、波士顿大学、东北大学、布朗大学和达特茅斯医学院，数据管理由内森·克莱恩研究所进行。第一年的CTP是马萨诸塞州牙买加平原的福克纳医院；马萨诸塞州丹弗斯的成瘾行为中心；马萨诸塞州伍斯特的AdCare医院；缅因州威斯布鲁克的仁慈医院康复中心；以及罗德岛州北金斯敦的SSTAR。另外四个CTP，包括新罕布夏州和佛蒙特州的CTP，有兴趣在第二年加入HUNNE节点。研究人员和CTP工作人员将相互合作，并与国家CTN人员合作，设计和实施CTP中的研究。HUNNE节点成员将进行其他节点开发的试验，并在此申请中提出两个可以在CTN全国范围内开展的研究概念。HUNNENode的主要目标是在社区项目中开发和开展药物滥用治疗研究。这些研究将确定各种治疗方法在广泛的治疗环境中的有效性。因此，CTN将有助于弥合成瘾研究和治疗社区之间的差距，从而提高药物依赖患者的整体治疗质量。

DESCRIPTION (provided by applicant): This is a proposal for a Harvard University Northern New England (HUNNE) Node for the NIDAClinical Trials Network (CTN). The proposed node is a partnership between academic researchers and clinical treatment programs (CTPs) in 5 New England states. The goal is to work together to design and implement addiction treatment studies in community programs so that patients receive the full benefit of the evolving science of addiction treatment. The HUNNE Node has expertise in the areas of behavioral, pharmacologic, combined behavioral/pharmacologic, and health services addictions research.Researchers for the HUNNE Node are based at Harvard University, Boston University, NortheasternUniversity, Brown University, and Dartmouth Medical School, with data management conducted at theNathan Kline Institute. The CTPs for Year One are Faulkner Hospital in Jamaica Plain, Massachusetts; the Center for Addictive Behaviors in Danvers, Massachusetts; AdCare Hospital in Worcester,Massachusetts; Mercy Hospital Recovery Center in Westbrook, Maine; and SSTAR of Rhode Island in North Kingston, Rhode Island. Four additional CTPs, including CTPs in New Hampshire and Vermont, are interested in joining the HUNNE Node in Year Two. Researchers and CTP staff will work together with one another and with national CTN personnel to design and implement studies in CTPs. HUNNE Node members will carry out trials developed by other nodes, and propose in this application tworesearch concepts that could be carried out nationwide in the CTN. The primary goal of the HUNNENode is to develop and carry out drug abuse treatment research studies in community programs. These studies will determine the effectiveness of a variety of treatment approaches in a broad range oftreatment settings. The CTN will thus help to bridge the gap between the addiction research and treatment communities, thus improving the overall quality of treatment for drug dependent patients.