CTN: Harvard University Northern New England Node

描述（由申请人提供）：这是一份关于哈佛大学新英格兰北部（HUNNE）节点的nid临床试验网络（CTN）的提案。提议的节点是新英格兰5个州的学术研究人员和临床治疗项目（ctp）之间的合作伙伴关系。目标是共同设计和实施社区项目中的成瘾治疗研究，使患者充分受益于不断发展的成瘾治疗科学。HUNNE节点在行为、药理学、行为/药理学结合和健康服务成瘾研究领域拥有专业知识。HUNNE节点的研究人员来自哈佛大学、波士顿大学、东北大学、布朗大学和达特茅斯医学院，数据管理由纳森克莱恩研究所进行。第一年的ctp是马萨诸塞州牙买加平原的福克纳医院；马萨诸塞州丹佛斯的成瘾行为研究中心；马萨诸塞州伍斯特的AdCare医院；缅因州韦斯特布鲁克慈善医院康复中心；以及罗德岛州北金斯敦的罗德岛州SSTAR。另外四个ctp，包括新罕布什尔州和佛蒙特州的ctp，有兴趣在第二年加入HUNNE节点。研究人员和CTP工作人员将相互合作，并与国家CTN人员合作，设计和实施CTP研究。HUNNE节点成员将进行其他节点开发的试验，并在此申请中提出两个可以在CTN全国范围内开展的研究概念。HUNNENode的主要目标是在社区项目中发展和开展药物滥用治疗研究。这些研究将确定在广泛的治疗环境中各种治疗方法的有效性。因此，CTN将有助于弥合成瘾研究和治疗社区之间的差距，从而提高药物依赖患者的整体治疗质量。

DESCRIPTION (provided by applicant): This is a proposal for a Harvard University Northern New England (HUNNE) Node for the NIDAClinical Trials Network (CTN). The proposed node is a partnership between academic researchers and clinical treatment programs (CTPs) in 5 New England states. The goal is to work together to design and implement addiction treatment studies in community programs so that patients receive the full benefit of the evolving science of addiction treatment. The HUNNE Node has expertise in the areas of behavioral, pharmacologic, combined behavioral/pharmacologic, and health services addictions research.Researchers for the HUNNE Node are based at Harvard University, Boston University, NortheasternUniversity, Brown University, and Dartmouth Medical School, with data management conducted at theNathan Kline Institute. The CTPs for Year One are Faulkner Hospital in Jamaica Plain, Massachusetts; the Center for Addictive Behaviors in Danvers, Massachusetts; AdCare Hospital in Worcester,Massachusetts; Mercy Hospital Recovery Center in Westbrook, Maine; and SSTAR of Rhode Island in North Kingston, Rhode Island. Four additional CTPs, including CTPs in New Hampshire and Vermont, are interested in joining the HUNNE Node in Year Two. Researchers and CTP staff will work together with one another and with national CTN personnel to design and implement studies in CTPs. HUNNE Node members will carry out trials developed by other nodes, and propose in this application tworesearch concepts that could be carried out nationwide in the CTN. The primary goal of the HUNNENode is to develop and carry out drug abuse treatment research studies in community programs. These studies will determine the effectiveness of a variety of treatment approaches in a broad range oftreatment settings. The CTN will thus help to bridge the gap between the addiction research and treatment communities, thus improving the overall quality of treatment for drug dependent patients.