CTN: Harvard University Northern New England Node

CTN：哈佛大学北新英格兰节点

• 批准号: 7384300
• 负责人: Roger D. Weiss
• 金额: $ 97.62万
• 依托单位: MCLEAN HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2007-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7384300
• 关键词: Abstinence; Academy; Accreditation; Acculturation; Acting Out; Acute; Addictive Behavior; Address; Adherence; Administrator; Admission activity; Adolescence; Adolescent; Adopted; Adoption; Adult; Adverse drug effect; Adverse effects; Adverse event; Adverse reactions; Advisory Committees; Advocacy; Advocate; Affect; Affective; African American; Aftercare; Age; Agonist; Agreement; Alcohol abuse; Alcohol consumption; Alcohol dependence; Alcohol or Other Drugs use; Alcoholism; Alcohols; Algorithms; All Sites; Allergic Reaction; American; Animal Model; Anxiety; Anxiety Disorders; Appendix; Appointment; Archives; Area; Arts; Asians; Attention; Attitude; Audiotape; Automobile Driving; Award; Awareness; Back; Beds; Behavior; Behavior Therapy; Behavioral; Behavioral Model; Belief; Benzodiazepines; Bilirubin; Binding Sites; Biological; Bipolar Disorder; Boston; Brain Injuries; Brain imaging; Budgets; Buprenorphine; Businesses; Calendar; California; Caring; Case Management; Case Report Form; 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ABSTRACT This is a proposal for a Harvard University Northern New England (HUNNE) Node for the NIDA Clinical Trials Network (CTN). The proposed node is a partnership between academic researchers and clinical treatment programs (CTPs) in 5 New England states. The goal is to work together to design and implement addiction treatment studies in community programs so that patients receive the full benefit of the evolving science of addiction treatment. The HUNNE Node has expertise in the areas of behavioral, pharmacologic, combined behavioral/pharmacologic, and health services addictions research. Researchers for the HUNNE Node are based at Harvard University, Boston University, Northeastern University, Brown University, and Dartmouth Medical School, with data management conducted at the Nathan Kline Institute. The CTPs for Year One are Faulkner Hospital in Jamaica Plain, Massachusetts; the Center for Addictive Behaviors in Danvers, Massachusetts; AdCare Hospital in Worcester, Massachusetts; Mercy Hospital Recovery Center in Westbrook, Maine; and SSTAR of Rhode Island in North Kingston, Rhode Island. Four additional CTPs, including CTPs in New Hampshire and Vermont, are interested in joining the HUNNE Node in Year Two. Researchers and CTP staff will work together with one another and with national CTN personnel to design and implement studies in CTPs. HUNNE Node members will carry out trials developed by other nodes, and propose in this application two research concepts that could be carried out nationwide in the CTN. The primary goal of the HUNNE Node is to develop and carry out drug abuse treatment research studies in community programs. These studies will determine the effectiveness of a variety of treatment approaches in a broad range of treatment settings. The CTN will thus help to bridge the gap between the addiction research and treatment communities, thus improving the overall quality of treatment for drug dependent patients.

摘要 这是一份为NIDA建立哈佛大学北方新英格兰（HUNNE）节点的提案 临床试验网络（CTN）。拟议的节点是学术研究人员之间的伙伴关系， 临床治疗计划（CTP）在5个新英格兰州。我们的目标是共同努力设计和 在社区项目中实施成瘾治疗研究，使患者充分受益， 不断发展的戒毒科学HUNNE节点在行为， 药理学、行为/药理学联合研究和卫生服务成瘾研究。 HUNNE节点的研究人员来自哈佛大学、波士顿大学和东北大学。 布朗大学和达特茅斯医学院，数据管理在 内森·克莱恩研究所。第一年的现金转拨方案是马萨诸塞州牙买加平原的福克纳医院; 马萨诸塞州丹弗斯的成瘾行为中心;伍斯特的AdCare医院， 马萨诸塞州;缅因州韦斯特布鲁克的Mercy医院康复中心;罗得岛的SSTAR 北金斯顿，罗得岛。另外四个现金转拨方案，包括新罕布什尔州和佛蒙特州的现金转拨方案， 有兴趣在第二年加入HUNNE节点。研究人员和CTP工作人员将共同努力 与国家现金转拨方案工作人员合作，设计和实施现金转拨方案研究。HUNNE 节点成员将进行其他节点开发的试验，并在本申请中提出两个 可以在CTN全国范围内开展的研究概念。HUNNE的主要目标 节点是在社区项目中开发和开展药物滥用治疗研究。这些 研究将确定各种治疗方法的有效性， 治疗设置。因此，CTN将有助于弥合成瘾研究与药物滥用之间的差距。 这将有助于提高药物依赖治疗社区的整体质量，从而提高药物依赖患者的治疗质量。