CELL AND MOLECULAR BIOLOGY OF DEVELOPMENT

描述(由申请人提供)：本申请寻求一个非常成功的CHRCDA的续签，它支持在华盛顿大学医学院儿科学习分子和细胞发育方面的儿科科学家的过渡性培训。该计划的目标是通过促进有前途的新儿科医生获得开始独立调查职业所需的教育、技能和经验来识别、鼓励和支持他们。新的研究人员和高级教师顾问在该大学及其附属机构、儿童医院和地区医学中心以及弗雷德·哈钦森癌症研究中心设有实验室，儿科系在这些中心建立了临床和研究项目。项目主任监督CHRCDA及其核心实验室的日常运作。核心实验室为CHRCDA新的研究人员和某些集中服务(例如转基因小鼠)提供了重点。核心实验室还充分利用了每个机构广泛共享的资源和设施。该计划的申请者有两个主要来源：儿科内部的研究金计划和积极的外部招聘。特别重视培养女儿科科学家的职业生涯，并确定了新的努力，以招募少数族裔受训人员到该部门及其CHRCDA。来自该计划的支持将是确保新的儿科研究人员有足够的受保护时间来获得和巩固他们成功竞争NIH和类似实体的个人研究奖所需的技能的桥梁。

DESCRIPTION (provided by applicant): This application seeks renewal of a highly successful CHRCDA, which supports the transitional training of pediatric scientists studying molecular and cellular aspects of development in the Department of Pediatrics, University of Washington School of Medicine. The objectives of this program are to identify, encourage, and support promising new pediatricians by facilitating their acquisition of the education, skills, and experience required to initiate independent investigative careers. The new investigators and senior faculty advisors have laboratories at the University and its affiliated institutions, the Children's Hospital & Regional Medical Center and Fred Hutchinson Cancer Research Center, where the Department of Pediatrics has established clinical and research programs. The Program Director oversees the day-to-day operations of the CHRCDA and its core laboratory. The core laboratory provides a focus for the CHRCDA new investigators and certain centralized services (e.g., transgenic mice). The core laboratory also takes full advantage of the extensive shared resources and facilities at each institution. There are two major sources of applicants to the program: fellowship programs within the Department of Pediatrics and active external recruitment. Particular emphasis is paid to nurturing the careers of female pediatric scientists, and new efforts have been identified to recruit minority trainees to the department and its CHRCDA. Support from this program will be the bridge that assures sufficient protected time for new pediatric investigators to acquire and consolidate the skills needed for them to successfully compete for individual research awards from the NIH and similar entities.