CELL AND MOLECULAR BIOLOGY OF DEVELOPMENT

描述（由申请人提供）：本申请寻求更新一个非常成功的CHRCDA，该申请支持华盛顿大学医学院儿科学系研究发育的分子和细胞方面的儿科科学家的过渡培训。该计划的目标是通过促进有前途的新儿科医生获得独立调查职业所需的教育，技能和经验，来识别，鼓励和支持他们。新的研究人员和高级教师顾问在大学及其附属机构，儿童医院和地区医疗中心以及弗雷德哈钦森癌症研究中心设有实验室，儿科部门在那里建立了临床和研究项目。项目主任负责监督CHRCDA及其核心实验室的日常运作。核心实验室为CHRCDA的新研究人员和某些集中服务（如转基因小鼠）提供重点。核心实验室还充分利用了各机构广泛的共享资源和设施。该项目有两个主要的申请者来源：儿科部门的奖学金项目和积极的外部招聘。特别强调培养女儿科科学家的职业，并确定了新的努力，为该部门及其CHRCDA招募少数民族受训人员。这项计划的支持将成为桥梁，确保新的儿科研究人员有足够的保护时间来获得和巩固他们成功竞争来自NIH和类似实体的个人研究奖励所需的技能。

DESCRIPTION (provided by applicant): This application seeks renewal of a highly successful CHRCDA, which supports the transitional training of pediatric scientists studying molecular and cellular aspects of development in the Department of Pediatrics, University of Washington School of Medicine. The objectives of this program are to identify, encourage, and support promising new pediatricians by facilitating their acquisition of the education, skills, and experience required to initiate independent investigative careers. The new investigators and senior faculty advisors have laboratories at the University and its affiliated institutions, the Children's Hospital & Regional Medical Center and Fred Hutchinson Cancer Research Center, where the Department of Pediatrics has established clinical and research programs. The Program Director oversees the day-to-day operations of the CHRCDA and its core laboratory. The core laboratory provides a focus for the CHRCDA new investigators and certain centralized services (e.g., transgenic mice). The core laboratory also takes full advantage of the extensive shared resources and facilities at each institution. There are two major sources of applicants to the program: fellowship programs within the Department of Pediatrics and active external recruitment. Particular emphasis is paid to nurturing the careers of female pediatric scientists, and new efforts have been identified to recruit minority trainees to the department and its CHRCDA. Support from this program will be the bridge that assures sufficient protected time for new pediatric investigators to acquire and consolidate the skills needed for them to successfully compete for individual research awards from the NIH and similar entities.