Functional Neurogenesis in the Injured Neocortex of the Nonhuman Primate

非人类灵长类动物受损新皮质的功能性神经发生

• 批准号: nhmrc : 1057698
• 负责人: A/Pr James Bourne
• 金额: $ 64.42万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/functional-neurogenesis-injured-nonhuman-primate/454622
• 关键词: Functional; Neurogenesis; Injured; Neocortex; Nonhuman

Research over the past couple of decades has revolutionised our understanding of the capacity of the brain to generate new cells, especially following an injury. However, what does remain controversial is whether this phenomenon occurs in all areas of the brain, especially following a severe traumatic brain injury or stroke. This project will examine whether the outer surface of the brain has the potential to generate new cells following a brain injury and whether they become functional.

过去几十年的研究彻底改变了我们对大脑产生新细胞能力的理解，特别是在受伤后。然而，仍然存在争议的是这种现象是否发生在大脑的所有区域，特别是在严重的创伤性脑损伤或中风之后。该项目将研究大脑的外表面是否有潜力在脑损伤后产生新的细胞，以及它们是否具有功能。