Support for Enhancement Excellence in Research at UPR-RP

支持 UPR-RP 提高卓越研究水平

• 批准号: 6959592
• 负责人: RAFAEL ARCE
• 金额: $ 36.97万
• 依托单位: UNIVERSITY OF PUERTO RICO RIO PIEDRAS
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-07-01 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6959592
• 关键词: Support; Enhancement; Excellence; Research; UPR

DESCRIPTION (provided by applicant): This supplemental application requests the addition of four new projects to the SCORE Program currently active at the University of Puerto Rico, Rio Piedras. The projects included are three from the Department of Biology and one from Chemistry. One from Biology (Maldonado) and another from Chemistry (Rodriguez) are revised applications according to the critiques reported in the summary statement for our SCORE application. Another is presented from a recently hired microbiologist (Dominguez) and the other is from an experienced investigator that participated in the previous grant cycle (Renaud). All together complement biomedical research efforts at UPR-RP that have been ongoing for over 32 years under the auspicies of the MBRS program and specifically, strengthen the present SCORE Program which groups 14 regular and 3 pilot projects (10 in Chemistry, 5 in Biology and 2 in Mathematics). Together these new projects aim to conduct competitive research in areas related to: biodemographic diversity of Helicobacter pylori in Latin America (Dominguez), the role of glutamate in drug conditioning (Maldonado), the effect of opiate withdrawal on human macrophages (Renaud), and novel anticancer and antibacterial drugs from Caribbean marine invertebrates (Rodriguez). These investigations are to be sustained by an ongoing administrative project and by technical and support personnel that include four laboratory technicians and three postdoctoral associates. This enhanced SCORE Program will provide this institution first-rate research and development opportunities as well as a fully supportive research atmosphere and will thus help the participating faculty to increase their biomedical research productivity, scientific competitiveness and peer recognition. Research activities in the program also enhance the existing MARC U*STAR Program and the MBRS-RISE Program at this institution. Progress in the specific aims of each new project and in the overall aims of the program will be evaluated yearly through an established Evaluation Plan.

描述（由申请人提供）：本补充申请要求增加四个新的项目，以SCORE计划目前活跃在波多黎各大学，里约热内卢皮德拉斯。其中包括三个来自生物系的项目和一个来自化学系的项目。一个来自生物学（马尔多纳多），另一个来自化学（罗德里格斯）是根据我们的SCORE应用程序的摘要声明中报告的评论修改的应用程序。另一份来自最近聘请的微生物学家（Dominguez），另一份来自参加过上一个资助周期的经验丰富的调查员（Renaud）。所有这些都补充了UPR-RP的生物医学研究工作，这些研究工作在MBRS计划的支持下已经持续了32年，特别是加强了目前的SCORE计划，该计划包括14个常规项目和3个试点项目（10个化学项目，5个生物项目和2个数学项目）。这些新项目旨在在以下相关领域开展竞争性研究：拉丁美洲幽门螺杆菌的生物人口多样性（Dominguez）、谷氨酸盐在药物调节中的作用（马尔多纳多）、阿片类药物戒断对人类巨噬细胞的影响（Renaud）以及加勒比海无脊椎动物的新型抗癌和抗菌药物（Rodriguez）。 这些调查将由一个正在进行的行政项目和技术和支助人员维持，其中包括四名实验室技术人员和三名博士后助理。这一增强的SCORE计划将为该机构提供一流的研究和开发机会以及充分支持的研究氛围，从而帮助参与的教师提高他们的生物医学研究生产力，科学竞争力和同行认可。该计划的研究活动也加强了该机构现有的MARC U* 星星计划和MBRS-RISE计划。每个新项目的具体目标和方案总体目标的进展情况将通过既定的评估计划每年进行评估。