Gabapentin in the treatment of idiopathic chronic cough: a randomised double-blind placebo-controlled trial

加巴喷丁治疗特发性慢性咳嗽：一项随机双盲安慰剂对照试验

• 批准号: nhmrc : 631066
• 负责人: Prof Peter Gibson
• 金额: $ 22.09万
• 依托单位: The University of Newcastle
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/gabapentin-treatment-idiopathic-controlled-trial/98137
• 关键词: Gabapentin; treatment; idiopathic; chronic; cough

Better treatment approaches are needed to address the significant quality of life impairment associated with chronic cough. We propose to conduct a double-blind, placebo controlled study comparing the efficacy (and safety) of oral gabapentin therapy on cough reflex severity and cough-specific quality of life in people with idiopathic cough. The advantages are a strong design, use of objective assessment techniques, and investigation of a new treatment modality for cough.

需要更好的治疗方法来解决与慢性咳嗽相关的严重生活质量损害。我们建议进行一项双盲、安慰剂对照研究，比较口服加巴喷丁治疗对特发性咳嗽患者咳嗽反射严重程度和咳嗽特异性生活质量的疗效（和安全性）。其优点是强大的设计，使用客观的评估技术，并调查了一种新的治疗咳嗽的方式。