CoCr/TiN Superlattice Hard Coatings for Spinal Implants

用于脊柱植入物的 CoCr/TiN 超晶格硬质涂层

• 批准号: 7053979
• 负责人: JASON E BURNS
• 金额: $ 16.91万
• 依托单位: SPIRE CORPORATION
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-08-01 至 2008-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7053979
• 关键词: hardness; implant

DESCRIPTION (provided by applicant): Title: CoCr/TiN Superlattice Hard Coatings for Spinal Implants: The objective of this program is to develop a hard, wear resistant TiN/CoCr coating for Ti or CoCr spinal implants with the benefits of a superlattice structure. Superlattices are thin films comprised of many alternating layers of materials with differing mechanical properties. A super-hardening phenomenon occurs when the layer spacing is in a specific range. For most materials, this occurs at lattice spacings from 5-15 nm. The mechanical properties of these nano-scaled structures are very different than those of monolithically grown coatings of the same constituents. In addition to improved hardness, superlattices exhibit an unusual wear mechanism which controls defect propagation and reduces the size of wear pits and debris. These unique properties are not intrinsic to the materials; rather they are a result of how the materials are arranged and the nano-scale of the structure. This new wear surface technology is well suited to protect orthopedic implants from excess wear. We will develop the constituent base material processes and the technology required to control multiple layer thicknesses at the nano-scale. TiN/CoCr superlattices of varying lattice spacing will be grown and the characteristic lattice spacing determined. We will develop an understanding of the wear properties of a TiN/CoCr superlattice as a function of lattice spacing, and we will be able to demonstrate how the wear properties are inherent to the nano-scaled laminar structure rather than simply the grain structure of the layered materials. Then, we will wear test coupons with peak and non-peak lattice spacings and compare them against coatings of monolithically grown TiN, CoCr, and a composite of TiN-CoCr. We expect to demonstrate significant reduction in wear of polyethylene in bench top tribological tests. Work in this program will lead to coating real implants for simulation tests in a Phase II grant. Ultimately, this work will allow us to offer a commercially viable coating to the orthopedic community. We expect that applying nano-scale layered coating systems known as superlattices to spinal implants will significantly extend their useful life. Our hope is that by improving implant life expectancy we can help make disk replacement implants a competitive alternative to fusion techniques, and expand the population of patients that can benefit from these devices.

描述（由申请人提供）：标题：脊柱植入物用CoCr/TiN超晶格硬质涂层：本项目的目的是开发具有超晶格结构优势的Ti或CoCr脊柱植入物用硬质耐磨TiN/CoCr涂层。超晶格是由许多具有不同机械性能的材料交替层组成的薄膜。当层间距在特定范围内时，发生超硬化现象。对于大多数材料，这发生在5-15 nm的晶格间距处。这些纳米级结构的机械性能与相同成分的单片生长涂层的机械性能非常不同。除了提高硬度外，超晶格还表现出一种不寻常的磨损机制，可以控制缺陷的传播并减小磨损坑和碎片的尺寸。这些独特的性质不是材料固有的;相反，它们是材料如何排列和结构的纳米尺度的结果。这种新的磨损表面技术非常适合保护骨科植入物免受过度磨损。我们将开发构成基础材料的工艺和在纳米尺度上控制多层厚度所需的技术。TiN/CoCr超晶格的不同的晶格间距将生长和确定的特征晶格间距。我们将发展的TiN/CoCr超晶格的晶格间距的函数的磨损性能的理解，我们将能够证明如何磨损性能是固有的纳米尺度的层状结构，而不是简单的层状材料的晶粒结构。然后，我们将磨损具有峰值和非峰值晶格间距的试样，并将它们与单片生长的TiN、CoCr和TiN-CoCr复合材料的涂层进行比较。我们希望在台架摩擦学试验中证明聚乙烯的磨损显著降低。这项计划的工作将导致涂层真实的植入物的模拟测试在第二阶段的赠款。最终，这项工作将使我们能够为骨科社区提供商业上可行的涂层。我们预计，将纳米级的层状涂层系统（称为超晶格）应用于脊柱植入物将显着延长其使用寿命。我们的希望是，通过提高植入物的预期寿命，我们可以帮助使椎间盘置换植入物成为融合技术的一种有竞争力的替代方案，并扩大可以从这些器械中受益的患者人群。