Gelsolin as a novel antiviral target

凝溶胶蛋白作为新型抗病毒靶点

• 批准号: nhmrc : 1043398
• 负责人: Dr Anthony Sadler
• 金额: $ 30.39万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/gelsolin-novel-antiviral-target/111572
• 关键词: Gelsolin; novel; antiviral; target

This proposal investigates processes that regulate the cell cytoskeleton to control shape and the dynamics membranes, with a view to developing a generic antiviral therapy. As viruses rely upon the cell cytoskeleton to initiate an infection, we posit that enzymes that control the cytoskeleton can be targeted to block infection.

该提案调查了调节细胞骨架以控制形状和动力学膜的过程，以期开发通用的抗病毒疗法。由于病毒依赖于细胞骨架来启动感染，我们认为可以靶向控制细胞骨架的酶来阻断感染。